| Type | Description |
|---|---|
| Definition | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 10:58:00 | The authors found that upregulation of Rbfox1, an RNA binding protein associated with intellectual disability, epilepsy and autism, increases selectively hippocampal TrkB.T1 isoform expression. Physiologically, increased Rbfox1 impairs BDNF-dependent LTP which can be rescued by genetically restoring TrkB.T1 levels. | 31429825 |
| 2019-12-14 11:25:00 | Rbfox deletion did not cause a reduction in global protein synthesis, but it led to altered splicing of hundreds of gene transcripts, including capn3, which produced an active form of calpain3 protease. | 29972780 |
| 2019-08-24 11:59:00 | The data imply Rbfox1 may be involved in the development of cardiomyopathies via regulating the alternative splicing of CaV1.2 exon 33. | 28949795 |
| 2019-08-17 12:15:00 | Rbfox1 is a regulator in the development of cortical interneuron-subtype-specific efferent connectivity. | 30318414 |
| 2019-07-20 10:09:00 | The regulation of interneuron-specific Vamp1 by Rbfox1 contributes to performance of specialized functions in defined neuronal subtypes. | 29621484 |
| Type | IDs |
|---|---|
| Synonymous | A2bp, A2bp1, Hrnbp1, fox-1 |
| Gene |
UniProtKB-ID:
RFOX1_MOUSE
UniprotKB:
Q9JJ43
UniParc:
UPI00001D9484,
UPI000050A0FD,
UPI00005ABB02,
UPI00001952FA,
UPI000050A0FE,
UPI000021584D,
UPI000050A0FC
EMBL:
AY659956,
AY659957,
AY659954,
AF107204,
AY659958,
AB041596,
AY659955,
AK134833,
AF191501,
BC059002
Ensembl:
ENSMUSG00000008658
KO:
mmu:268859
|
| Nucleutide sequences |
EMBL-CDS:
AAV74337.1,
AAH59002.1,
AAV74340.1,
BAE22304.1,
AAV74339.1,
AAV74341.1,
AAF78292.1,
AAV74338.1,
BAA95079.1,
AAL83425.1
Gene_ORFName:
MNCb-3035
Ensembl_TRS:
ENSMUST00000229741,
ENSMUST00000056416,
ENSMUST00000115841
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000155364,
ENSMUSP00000111507,
ENSMUSP00000049970
RefSeq:
XP_036015837.1,
NP_001346657.1,
XP_036015826.1,
XP_011244209.2,
XP_011244213.2,
XP_036015845.1,
NP_001346652.1,
XP_017172477.2,
XP_036015833.1,
XP_006522236.1,
XP_011244221.2,
XP_036015841.1,
XP_036015835.1,
XP_036015834.1,
XP_030104984.1,
XP_006522242.1,
XP_030104992.1,
XP_036015828.1,
XP_011244214.2,
NP_001346654.1,
XP_017172478.2,
XP_030104985.1,
XP_006522218.3,
XP_036015842.1,
NP_067452.2,
XP_030104983.1,
XP_030104988.1,
XP_036015838.1,
XP_036015829.1,
XP_036015836.1,
XP_017172488.1,
NP_899011.2,
XP_006522241.1,
XP_017172481.1,
XP_036015831.1,
XP_036015846.1,
XP_036015832.1,
XP_036015840.1,
NP_001346655.1,
NP_001346653.1,
XP_036015830.1,
XP_036015827.1,
XP_036015839.1,
XP_011244216.2,
XP_036015847.1,
XP_006522238.1,
XP_036015843.1,
NP_001346658.1,
XP_036015844.1,
XP_011244212.2,
XP_011244217.2,
NP_001346659.1,
XP_011244218.2
|
| Others |
UniRef100:
UniRef100_Q9JJ43
UniRef90:
UniRef90_Q9JJ43
UniRef50:
UniRef50_Q9JJ43
UniGene:
Mm.370334
CCDS:
CCDS37245.1,
CCDS27936.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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