| Type | Description |
|---|---|
| Definition | WD repeat and FYVE domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | WDFY2 Potentiates Hepatic Insulin Sensitivity and Controls Endosomal Localization of the Insulin Receptor and IRS1/2. | 32641353 |
| 2010-01-21 00:00:00 | Data show that ProF binds to Foxo1, a negative regulator of insulin action and adipogenesis, and facilitates the phosphorylation and thus inactivation of Foxo1 by Akt. | 18388859 |
| 2010-01-21 00:00:00 | The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and (protein kinase Czeta/lambda) via its WD-repeat propeller. | 16792529 |
| Type | IDs |
|---|---|
| Synonymous | 5830485M08, B130024L21Rik, ProF, ZFYVE22 |
| Gene |
UniProtKB-ID:
WDFY2_MOUSE
UniprotKB:
Q8BUB4
UniParc:
UPI0000021349
EMBL:
CH466535,
AK151817,
AK086275,
AK131958,
BC116632
Ensembl:
ENSMUSG00000014547
KO:
mmu:268752
|
| Nucleutide sequences |
EMBL-CDS:
BAC39640.1,
BAE20902.1,
BAE30714.1,
EDL36078.1,
AAI16633.1
Ensembl_TRS:
ENSMUST00000014691
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000014691
RefSeq:
NP_780755.2,
XP_036014505.1,
XP_036014504.1,
XP_006519127.1
|
| Others |
UniRef100:
UniRef100_Q8BUB4
UniRef90:
UniRef90_Q8BUB4
UniRef50:
UniRef50_Q8BUB4
UniGene:
Mm.1960,
Mm.416426,
Mm.482243
CCDS:
CCDS27192.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32641353 |
Diabetes Luyao Zhang , Xue Li , Nan Zhang , Xin Yang , Tianyun Hou , Wan Fu , Fengjie Yuan , Lina Wang , He Wen , Yuan Tian , Hongquan Zhang , Xifeng Lu , Wei-Guo Zhu |
2020-09-01 | - |
| 22988430 |
Front Neurosci Carrie B Wiese , Sara Ireland , Nicole L Fleming , Jing Yu , M Todd Valerius , Kylie Georgas , Han Sheng Chiu , Jane Brennan , Jane Armstrong , Melissa H Little , Andrew P McMahon , E Michelle Southard-Smith |
2012-01-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18388859 |
Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis. EMBO J. Thorsten Fritzius , Karin Moelling |
2008-05-07 |
Akt1,
Wdfy2,
Foxo1,
WDFY2
|
| 18287559 |
GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project |
2008-04-01 | - |
| 17313651 |
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. FEBS J. Thorsten Fritzius , Alexander D Frey , Marc Schweneker , Daniel Mayer , Karin Moelling |
2007-03-01 |
Prkci,
Prkcz,
Vamp2,
Wdfy2,
WDFY2,
PRKCI,
PRKCZ,
VAMP2
|
| 16792529 |
A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. Biochem. J. Thorsten Fritzius , Gabriela Burkard , Elvira Haas , Jochen Heinrich , Marc Schweneker , Magnus Bosse , Sven Zimmermann , Alexander D Frey , Antje Caelers , Andre S Bachmann , Karin Moelling |
2006-10-01 |
Akt1,
Akt2,
Prkci,
Prkcz,
Wdfy2,
WDFY2,
AKT1,
AKT2,
PRKCI,
PRKCZ
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 15618518 |
Mouse brain organization revealed through direct genome-scale TF expression analysis. Science Paul A Gray , Hui Fu , Ping Luo , Qing Zhao , Jing Yu , Annette Ferrari , Toyoaki Tenzen , Dong-In Yuk , Eric F Tsung , Zhaohui Cai , John A Alberta , Le-Ping Cheng , Yang Liu , Jan M Stenman , M Todd Valerius , Nathan Billings , Haesun A Kim , Michael E Greenberg , Andrew P McMahon , David H Rowitch , Charles D Stiles , Qiufu Ma |
2004-12-24 |
Zkscan16,
9130023H24Rik,
Srcap,
Zbtb48,
Akna,
Zfp729b,
Pds5b,
Dcun1d4,
Zfp513,
Zfp282,
Zfp956,
Trim68,
Champ1,
Zdhhc7,
Hinfp,
Zc3h10,
Zfp692,
Hoxb2,
Etv5,
Kdm3a,
Zfp120,
Zfp119a,
Isl2,
Barhl2,
Rcor2,
Rhox9,
E2f4,
Cbll1,
Rnf44,
Brd9,
Mbnl2,
Cphx1,
Tigd5,
Sharpin,
Prickle1,
Dhx57,
Tcf19,
Hmgxb3,
Otub1,
Lpxn,
Gbf1,
Atf5,
Ovol2,
Osr2,
Prrxl1,
Bmyc,
Jmjd6,
Whsc1,
Gcm2,
Chd4,
U2af1,
Foxp1,
Rnf187,
Zdhhc15,
Jmjd1c,
Ibtk,
Zzz3,
E2f8,
Sp110,
Uhrf2,
Rlf,
Rnf20,
Tbx10,
Lmo1,
Hoxc11,
Braf,
Mzf1,
Zfp91,
Zbtb25,
Dek,
Hivep1,
Prdm2,
Lmx1a,
Cse1l,
Nr3c2,
Tshz1,
Foxe1,
Lims1,
D17H6S56E-5,
Egln1,
C030039L03Rik,
2610305D13Rik,
Vmn1r50,
Foxp2,
Macf1,
Zbtb21,
Crip3,
Prdm15,
Brdt,
Ferd3l,
Vsx1,
Dcun1d1,
Adnp,
Aebp2,
Nr0b1,
Ahr,
Ahrr,
Aip,
Aire
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员