| Type | Description |
|---|---|
| Definition | piccolo (presynaptic cytomatrix protein) |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:37:00 | Loss of Piccolino, the synaptic ribbon specific splice variant of Piccolo, disrupts the characteristic plate-shaped structure of synaptic ribbons. | 30696732 |
| 2018-04-21 10:04:00 | Piccolo puncta sandwiched Bassoon puncta and aligned in a Piccolo-Bassoon-Piccolo structure in adult neuromuscular junctions (NMJs). P/Q-type voltage-gated calcium channel (VGCC) puncta colocalized with Bassoon puncta. The P/Q-type VGCC and Bassoon protein levels decreased significantly in NMJs from aged mouse. In contrast, the Piccolo levels in NMJs from aged mice were comparable to levels in adult mice. | 27321892 |
| 2014-04-05 13:48:00 | a function of Piccolino at ribbon synapses of sensory neurons | 23936420 |
| 2013-05-25 10:34:00 | a novel role for Bassoon and Piccolo as critical regulators of presynaptic ubiquitination and proteostasis. | 23403927 |
| 2011-11-19 11:50:00 | Piccolo is an important regulator of presynaptic F-actin, functioning to coordinate its activity-dependent assembly and thereby modulating neurotransmitter release. | 21976510 |
| Type | IDs |
|---|---|
| Synonymous | Acz, Pico |
| Gene |
UniProtKB-ID:
PCLO_MOUSE
UniprotKB:
Q9QYX7
UniParc:
UPI00015FA08D,
UPI00015FF5B0
EMBL:
AC144625,
Y19185,
AC144480,
AB083477,
AC125043,
Y19186,
AF181269,
AC125533,
AB083478
Ensembl:
ENSMUSG00000061601
KO:
mmu:26875
|
| Nucleutide sequences |
EMBL-CDS:
BAC53724.1,
AAD55786.2,
CAB60732.2,
CAB60731.2,
BAC53723.1
Ensembl_TRS:
ENSMUST00000182407,
ENSMUST00000030691
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030691,
ENSMUSP00000138419
RefSeq:
XP_036021038.1,
NP_001104266.1,
XP_006503646.2,
XP_036021039.1,
NP_036125.4,
XP_006503645.2,
XP_006503647.2
|
| Others |
UniRef100:
UniRef100_Q9QYX7
UniRef90:
UniRef90_Q9QYX7
UniRef50:
UniRef50_Q9JKS6
UniGene:
Mm.146275
CCDS:
CCDS51415.1,
CCDS59667.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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