| Type | Description |
|---|---|
| Definition | 5-oxoprolinase, ATP-hydrolysing |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:15:00 | An autosomal recessive mode of inheritance for 5-oxoprolinase deficiency is further supported by the identification of a single mutation in all 9/14 parent sample sets investigated (except for the father of one patient whose result suggests homozygosity), and the absence of 5-oxoprolinuria in all tested heterozygotes | 27477828 |
| 2016-07-16 11:34:00 | In this study, clinical, biochemical, and genetic aspects of five Chinese 5-oxoprolinuria patients with OPLAH or GSS gene mutations were investigated. | 25851806 |
| 2010-08-09 12:15:00 | the cause of cellular ATP depletion in nephrotic cystinosis may be the futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase | 20413906 |
| Type | IDs |
|---|---|
| Synonymous | 5-Opase, OPLA, OPLAHD |
| Gene |
UniProtKB-ID:
OPLA_HUMAN
UniprotKB:
O14841
UniParc:
UPI000035154E
EMBL:
AL096750,
BC142672,
AH005594,
AB122018
Ensembl:
ENSG00000178814
KO:
hsa:26873
|
| Nucleutide sequences |
EMBL-CDS:
CAB46426.2,
AAI42673.1,
BAD13434.1,
AAB81519.1
Ensembl_TRS:
ENST00000618853
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480476
RefSeq:
XP_011515262.1,
NP_060040.1
|
| Others |
UniRef100:
UniRef100_O14841
UniRef90:
UniRef90_O14841
UniRef50:
UniRef50_O14841
UniGene:
Hs.305882
CCDS:
CCDS75802.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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