| Type | Description |
|---|---|
| Definition | RNA, U1 small nuclear 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-18 13:41:00 | The authors show that U1 telescripting is selectively required for sustaining long-distance transcription elongation in introns of large genes (median 39 kb). | 28967884 |
| 2017-07-29 11:19:00 | We found that only the modified U1 snRNA (IVS-AAA) that completely matched both the intronic and exonic U1 binding sequences of the mutated DDC gene could correct splicing errors of either the mutated human DDC minigene or the mouse artificial splicing construct in vitro | 27658936 |
| 2017-06-24 12:44:00 | An imbalance in the vU1/U1 ratio, rather than an overall reduction in Uridyl-rich (U)-snRNAs, may contribute to the specific neuromuscular disease phenotype associated with spinal muscular atrophy. | 27536002 |
| 2014-05-24 10:05:00 | Human U1 snRNA variants are unable to efficiently bind U1 snRNP proteins. | 24583175 |
| 2012-11-24 10:13:00 | Authors propose that U1 shortage causes transcript shortening because, as cotranscriptional recruitment of U1 to nascent transcripts becomes limiting, it leaves distal polyadenylation signals less protected, providing a built-in and U1 dose-dependent mechanism for mRNA length regulation and isoform switching. | 22770214 |
| Type | IDs |
|---|---|
| Synonymous | HSD1, HU1-1, RNU1, RNU1A, RNU1A3, RNU1G4, Rnu1a1, U1, U1A1 |