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268566 Gphn

268566

Gphn

gephyrin

protein-coding

Mus musculus

基因描述

Type Description
Definition gephyrin

研究结论

Date Results Publications
2018-09-08 10:40:00 Study unravels the critical role for cellular signal transduction pathways in determining gephyrin SUMOylation, phosphorylation and acetylation at identified residues to regulate its scaffolding properties at specific postsynaptic sites and in turn regulating GABAergic function and plasticity. 27819299
2016-12-24 11:47:00 Ablation of gephyrin result in the forebrain-specific loss of postsynaptic gamma2-GABAA receptors, reduces LTP and network excitability in the dentate gyrus. 26829712
2016-06-11 11:11:00 adult mice lacking interleukin-1 receptor 1 (IL-1R1) exhibit increased expression of both the excitatory scaffolding protein postsynaptic density-95 (PSD-95) and inhibitory scaffolding proteingephyrin, respectively, in the hippocampus. 25263489
2016-05-21 12:34:00 The results demonstrate that formation of GABAergic synapses containing a postsynaptic gephyrin scaffold is crucial for morphological differentiation, synaptic integration, and long-term survival of adult-born granule cells/ 25772192
2015-09-26 14:12:00 Data suggest that KIF5 regulates gephyrin sorting by a mechanism that involves GSK3 activity. 25701174

名称对应

Type IDs
Synonymous 5730552E08Rik, AI662856, BC027112, C230040D23, GPH, GPHRYN, geph
Gene
UniProtKB-ID: GEPH_MOUSE, A0JNY3_MOUSE
UniprotKB: Q8BUV3, A0JNY3
UniParc: UPI0000354394, UPI000024E8ED
EMBL: BC127058, AC125057, AC124346, AC132097, AC124572, AK082353, AC148324
Ensembl: ENSMUSG00000047454
KO: mmu:268566
Nucleutide sequences
EMBL-CDS: BAC38476.1, AAI27059.1
Ensembl_TRS: ENSMUST00000052472, ENSMUST00000110388
Protein sequencees
Ensembl_PRO: ENSMUSP00000054064, ENSMUSP00000106018
RefSeq: XP_017170563.1, XP_017170569.1, XP_017170562.1, XP_006515962.1, XP_036013319.1, NP_766540.2, XP_006515964.1, XP_017170564.1, XP_006515966.1, XP_006515968.1, XP_017170568.1, XP_006515969.1, XP_006515970.1, XP_036013324.1, XP_036013318.1, XP_017170566.1, XP_006515967.1, NP_666077.2, XP_030102593.1, XP_030102590.1, XP_017170565.1, XP_036013323.1, XP_030102591.1, XP_006515965.1, XP_006515963.1, XP_030102592.1, XP_036013322.1, XP_036013321.1, XP_017170567.1
Others
UniRef100: UniRef100_Q8BUV3, UniRef100_A0JNY3
UniRef90: UniRef90_Q03555
UniRef50: UniRef50_Q03555
UniGene: Mm.341742, Mm.363753, Mm.453131
CCDS: CCDS26000.1

全选

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