| Type | Description |
|---|---|
| Definition | beta-1,4-galactosyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:28:00 | Study on the role and mechanism of beta4GalT1 both in vivo and in vitro glioma. | 32373974 |
| 2020-09-19 16:24:00 | beta4GalT1 promotes inflammation in human osteoarthritic fibroblast-like synoviocytes by enhancing autocrine TNF-alpha activity. | 31210280 |
| 2020-02-22 12:11:00 | B4GALT1 expression in stromal cells positively correlated with upstream c-Jun expression | 32027290 |
| 2019-04-06 10:11:00 | Study solved the crystal structure of the wild-type human B4GalT1 homodimer and showed that B4GalT1 exists in a dynamic equilibrium between monomer and dimer. These two crystal forms revealed the unliganded B4GalT1 in both the open and the closed conformation of the Trp loop and the lid regions, responsible for donor and acceptor substrate binding, respectively. | 30352055 |
| 2019-01-19 11:45:00 | Study indicated that B4GALT1 may be a possible prognosticator of muscle-invasive bladder cancer, and it may be a predictive marker for the choice of adjuvant chemotherapy in pT3/4 or N+ patients. | 29793447 |
| Type | IDs |
|---|---|
| Synonymous | B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1 |
| Gene |
UniProtKB-ID:
B4GT1_HUMAN
UniprotKB:
P15291
UniParc:
UPI000002D22E,
UPI0000052C0F
EMBL:
X13223,
M70430,
X55415,
M70431,
M22921,
M70429,
M70427,
D29805,
AL161445,
AK312797,
U10472,
U10473,
CH471071,
M13701,
X14085,
U10474,
M70432,
M70428
Ensembl:
ENSG00000086062
KO:
hsa:2683
|
| Nucleutide sequences |
EMBL-CDS:
AAA35936.1,
BAA06188.1,
AAA35935.1,
CAA39074.1,
CAA39073.1,
AAA68218.1,
AAA68219.1,
CAA32247.1,
BAG35657.1,
AAA35937.1,
AAB00776.1,
AAA68220.1,
CAA31611.1,
EAW58520.1,
EAW58521.1
Ensembl_TRS:
ENST00000379731
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369055
RefSeq:
NP_001488.2,
NP_001365426.1,
NP_001365424.1,
NP_001365425.1
|
| Others |
UniRef100:
UniRef100_P15291
UniRef90:
UniRef90_P15291
UniRef50:
UniRef50_P15291
UniGene:
Hs.272011
CCDS:
CCDS6535.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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