| Type | Description |
|---|---|
| Definition | GDNF family receptor alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRalpha1 for Specific Infection of Breast | 33233403 |
| 2021-01-09 13:34:00 | Hypomethylation of GDNF family receptor alpha 1 promotes epithelial-mesenchymal transition and predicts metastasis of colorectal cancer. | 33175846 |
| 2020-06-13 11:25:00 | GFRA1 expression is frequently reactivated by DNA demethylation in colon cancer (CC) tissues and is significantly associated with a poor prognosis in patients with CC, especially those with metastatic CC. GFRA1 can promote the proliferation/growth of CC cells, probably by the activation of AKT and ERK pathways. | 31988584 |
| 2019-11-16 12:36:00 | Low expression of EZH2 in the colon tissue of children with Hirschsprung's disease may be one of the causes of inadequate expression of GFRalpha1 and onset of Hirschsprung's disease | 31642440 |
| 2019-10-05 11:48:00 | Data suggest that GDNF family receptor alpha 1 protein (GFRA1) is a protein target of ST3 beta-galactoside alpha-23-sialyltransferase 1 (ST3GAL1). | 30040982 |
| Type | IDs |
|---|---|
| Synonymous | GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 |
| Gene |
UniProtKB-ID:
GFRA1_HUMAN,
B7Z856_HUMAN
UniprotKB:
P56159,
B7Z856
UniParc:
UPI0001915184,
UPI000002AA61,
UPI000012B3A8
EMBL:
AK302914,
AF038421,
AF038414,
AF058992,
AF058995,
AF038413,
AF058999,
AF038419,
AF038420,
AF038416,
U95847,
AF038412,
AF058994,
AK292886,
AF042080,
AF038418,
BC014962,
AF038417,
AF058991,
AF058997,
AF038411,
CH471066,
AF058998,
U97144,
AF038415,
AF058990,
AF058996,
AF058993
Ensembl:
ENSG00000151892
KO:
hsa:2674
|
| Nucleutide sequences |
EMBL-CDS:
AAC14431.1,
AAC51646.1,
BAF85575.1,
AAB97371.1,
AAB71811.1,
EAW49458.1,
AAC39692.1,
AAH14962.1,
AAC39693.1,
BAH13842.1
Ensembl_TRS:
ENST00000355422,
ENST00000439649,
ENST00000369234,
ENST00000369236
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358237,
ENSP00000347591,
ENSP00000358239,
ENSP00000393725
RefSeq:
XP_011537936.1,
NP_001369486.1,
NP_001138925.1,
NP_001369490.1,
NP_001335028.1,
NP_001369489.1,
NP_001369487.1,
NP_001369488.1,
NP_001369485.1,
NP_001335027.1,
NP_665736.1,
NP_005255.1,
NP_001335025.1
|
| Others |
UniRef100:
UniRef100_P56159,
UniRef100_B7Z856
UniRef90:
UniRef90_B7Z856,
UniRef90_P56159
UniRef50:
UniRef50_A0A1L8FI88,
UniRef50_P56159
UniGene:
Hs.388347
CCDS:
CCDS44481.1,
CCDS7593.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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