| Type | Description |
|---|---|
| Definition | glutamine--fructose-6-phosphate transaminase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:39:00 | GFAT1/HBP/O-GlcNAcylation Axis Regulates beta-Catenin Activity to Promote Pancreatic Cancer Aggressiveness. | 32149084 |
| 2020-05-23 10:53:00 | The longevity-associated G451E of GFAT1 variant shows drastically reduced sensitivity to UDP-GlcNAc inhibition. | 32019926 |
| 2019-11-30 10:54:00 | GFPT1 variants and defects in other enzymes of this pathway have previously been associated with congenital myasthenia. These findings identify leukoencephalopathy as a previously unrecognized phenotype in GFPT1-related disease and suggest that mitochondrial dysfunction could contribute to this disorder. | 30635494 |
| 2019-05-18 10:10:00 | These results suggest that 2-deoxy-d-glucose reduces N-glycosylation of proteins following the increase of phosphorylation of GFAT1 and results in the inhibition of cell growth mediated by endoplasmic reticulum stress in pancreatic cancer cells. | 29753740 |
| 2019-05-11 13:07:00 | MTOR2/C-MYC/GFAT1 axis is responsible for the modulation on the crosstalk between glycolysis and glutaminolysis in glioblastoma cells. | 30771196 |
| Type | IDs |
|---|---|
| Synonymous | CMS12, CMSTA1, GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG |
| Gene |
UniProtKB-ID:
GFPT1_HUMAN
UniprotKB:
Q06210
UniParc:
UPI000015C8AD,
UPI000000DB00
EMBL:
BC045641,
AF334737,
M90516,
AC114772
Ensembl:
ENSG00000198380
KO:
hsa:2673
|
| Nucleutide sequences |
EMBL-CDS:
AAK15342.1,
AAA58502.1,
AAY14827.1,
AAH45641.1
Ensembl_TRS:
ENST00000361060,
ENST00000357308
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354347,
ENSP00000349860
RefSeq:
NP_001231639.1,
XP_016859291.1,
NP_002047.2,
XP_016859290.1
|
| Others |
UniRef100:
UniRef100_Q06210
UniRef90:
UniRef90_Q06210
UniRef50:
UniRef50_Q06210
UniGene:
Hs.580300
CCDS:
CCDS33216.1,
CCDS58713.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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