| Type | Description |
|---|---|
| Definition | growth factor, augmenter of liver regeneration |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 12:40:00 | Downregulation of WW domain-containing oxidoreductase leads to tamoxifen-resistance by the inactivation of Hippo signaling. | 31155927 |
| 2020-05-09 12:16:00 | Augmenter of liver regeneration (ALR) gene transfection alleviates mitochondrial injury, through inhibiting fission and promoting fusion of the mitochondrial inner membrane, both of which contribute to reduction of HK-2 cell apoptosis. Additionally, fission processes are mediated by promoting tubular cell survival through activating the mTOR/4E-BP1 signaling pathway. | 31822044 |
| 2020-05-09 12:02:00 | High levels of cytosolic short form of ALR reduced CYP7A1 mRNA expression and bile acids levels attributed to activation. | 30500391 |
| 2020-03-21 11:20:00 | This study finds a previously unrecognized role of RASSF1A in the regulation of CTGF and CYR61 through mediation of Hippo pathway in UBC and supports the significance of this link as a potential therapeutic target for UBC. | 31754973 |
| 2020-02-01 10:25:00 | Results found that TGF-beta induced miRNA-181a, which in turn induced liver fibrosis, at least in part, by inhibiting ALR. ALR inhibited TGF-beta action by decreasing the expression of TGFbeta-RII, thereby inhibiting miRNA-181a expression and fibrosis markers. | 31166951 |
| Type | IDs |
|---|---|
| Synonymous | ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS |
| Gene |
UniProtKB-ID:
ALR_HUMAN
UniprotKB:
P55789
UniParc:
UPI0000140A12,
UPI0000000285
EMBL:
BC028348,
AF306863,
BC002429,
AF146394,
AF124604,
AC005606,
U31176,
AY550027,
AF183892
Ensembl:
ENSG00000127554
KO:
hsa:2671
|
| Nucleutide sequences |
EMBL-CDS:
AAD17328.1,
AAH02429.1,
AAH28348.2,
AAA96390.2,
AAD56538.1,
AAG38105.1,
AAD36986.1,
AAS55642.1
Ensembl_TRS:
ENST00000248114
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000248114
RefSeq:
NP_005253.3
|
| Others |
UniRef100:
UniRef100_P55789
UniRef90:
UniRef90_P55789
UniRef50:
UniRef50_P55789
UniGene:
Hs.27184
CCDS:
CCDS32368.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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