| Type | Description |
|---|---|
| Definition | autocrine motility factor receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 14:02:00 | Results report that GP78 physically interacts with and promotes DUSP1 ubiquitination and its subsequent degradation. Notably, GP78 mediates downregulation of DUSP1 expression while EGF-mediated ERK signaling. | 31061093 |
| 2019-10-26 12:14:00 | The study unveils a previously unknown function of USP34 in regulating the metabolic stability of gp78. | 30585151 |
| 2019-10-05 10:35:00 | ER stress treatment generates a marginal increase in Gp78 endogenous levels, and this elevation effect was prominent for intracellular accumulation of p27 in cells. Taken together, our current findings suggest a valuable multifactorial regulatory mechanism and linkage of p27 with UPS pathway | 29741771 |
| 2018-09-29 10:12:00 | There was a significant correlation between the 145 locus of the gp89 gene and coronary atherosclerotic heart disease, indexes of blood fat, blood glucose and blood pressure. | 28212872 |
| 2017-12-09 13:36:00 | This is the first study to show that mediated HIF-1alpha stabilization. In addition, this is the first study to show that GP78 inactivation promotes cancer cell proliferation, migration and eventual tumor growth both in vivo and in vitro by increasing cellular prion protein. | 28759037 |
| Type | IDs |
|---|---|
| Synonymous | GP78, RNF45 |
| Gene |
UniProtKB-ID:
AMFR_HUMAN,
A0A024R6R5_HUMAN
UniprotKB:
Q9UKV5,
A0A024R6R5
UniParc:
UPI000013EDCA,
UPI0000EE57CE
EMBL:
L35233,
AF124145,
CH471092,
M63175,
BC069197
Ensembl:
ENSG00000159461
KO:
hsa:267
|
| Nucleutide sequences |
EMBL-CDS:
AAH69197.1,
AAD56722.1,
AAA79362.1,
AAA36671.1,
EAW82858.1,
EAW82857.1
Gene_ORFName:
hCG_1811773
Ensembl_TRS:
ENST00000290649
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000290649
RefSeq:
XP_005255947.1,
NP_001310440.1,
NP_001135.3,
NP_001310441.1
|
| Others |
UniRef100:
UniRef100_Q9UKV5
UniRef90:
UniRef90_Q9UKV5
UniRef50:
UniRef50_Q9UKV5
UniGene:
Hs.295137
CCDS:
CCDS10758.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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