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266977 ADGRF1

266977

ADGRF1

adhesion G protein-coupled receptor F1

protein-coding

Homo sapiens

基因描述

Type Description
Definition adhesion G protein-coupled receptor F1

研究结论

Date Results Publications
2019-06-29 11:31:00 This signaling pathway leads to the expression of neurogenic and synaptogenic genes and suppresses the expression of proinflammatory genes. The GPR110-dependent cellular effects of synaptamide are recapitulated in animal models, suggesting that synaptamide-derived mechanisms may have translational implications. 29572109
2019-04-13 10:32:00 Our study revealed that high expression of GPR110 predicts the poor prognosis of gastric cancer patients, and GPTR110 may function as a potential biomarker for the diagnosis of gastric cancer. 30638950
2019-03-09 12:39:00 we found that GPR110 knockdown significantly reduced anchorage-dependent/independent cell growth as well as migration/invasion of parental and LTR cells and mammosphere formation in LTR derivatives and not in parental cells. 29574636
2018-09-08 11:24:00 Study demonstrated orphan G-protein coupled receptor 110 (GPR110, ADGRF1) as the synaptamide receptor, mediating synaptamide-induced bioactivity in a cAMP-dependent manner. 27759003
2017-11-04 12:38:00 High GPR110 expression is associated with CRLF2-rearranged acute lymphoblastic leukemia. 28866095

名称对应

Type IDs
Synonymous GPR110, KPG_012, PGR19, hGPCR36
Gene
UniProtKB-ID: AGRF1_HUMAN, Q3SXM8_HUMAN
UniprotKB: Q5T601, Q3SXM8
UniParc: UPI00005B72BD, UPI00000474ED, UPI000013D07E
EMBL: AB045123, AL355518, AY140952, AY255595, AK055208, AK026337, BC113634, BC113636, BC104214, CH471081, AB065679
Ensembl: ENSG00000153292
KO: hsa:266977
Nucleutide sequences
EMBL-CDS: AAO85107.1, CAI13873.1, BAB15452.1, CAI13874.1, AAI13637.1, CAI13875.1, AAN46666.1, EAX04311.1, AAI13635.1, BAB70874.1, BAD83599.1, BAC45260.1, AAI04215.1
Ensembl_TRS: ENST00000371243, ENST00000371253
Protein sequencees
Ensembl_PRO: ENSP00000360289, ENSP00000360299
RefSeq: NP_079324.2, XP_011512771.1, XP_016866225.1, NP_722582.2, XP_024302169.1, XP_016866224.1
Others
UniRef100: UniRef100_Q5T601, UniRef100_Q3SXM8
UniRef90: UniRef90_Q5T601, UniRef90_Q3SXM8
UniRef50: UniRef50_Q5T601, UniRef50_Q3SXM8
UniGene: Hs.733762
CCDS: CCDS4920.1, CCDS34471.1

全选

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