tlx1 - T cell leukemia homeobox 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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266964 tlx1

基因描述

Type	Description
Definition	T cell leukemia homeobox 1

研究结论

Date	Results	Publications
2020-04-25 11:58:00	Our data suggest that tlx1 is a crucial regulator of spleen development in fish, as it is in mammals.	31678534
2010-03-01 11:19:00	Detrmination site by nested polymerase chain reaction the integration sites in TLX1-immortalized hematopoietic cell lines.	19862821
2010-01-21 00:00:00	identification and expression patterns of three members of the zebrafish Tlx family	12204264

名称对应

Type	IDs
Synonymous	SI:dZ46P4.1, Tlx-1, hox11, ztlx-1
Gene	UniProtKB-ID: Q8JI13_DANRE UniprotKB: Q8JI13 UniParc: UPI00000FC1B6 EMBL: BX950184, AL929231, AF398517, AL928816, BC162115, BC162486 Ensembl: ENSDARG00000003965 KO: dre:266964
Nucleutide sequences	EMBL-CDS: AAI62486.1, AAM90622.1, CAE49441.1, AAI62115.1, CAE50907.1 Gene_ORFName: tlx1-001-2, tlx1-001 Ensembl_TRS: ENSDART00000006393
Protein sequencees	Ensembl_PRO: ENSDARP00000003103 RefSeq: NP_739571.1
Others	UniRef100: UniRef100_Q8JI13 UniRef90: UniRef90_Q8JI13 UniRef50: UniRef50_Q61663 UniGene: Dr.18844

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31678534	Congenital asplenia due to a tlx1 mutation reduces resistance to Aeromonas hydrophila infection in zebrafish. Fish Shellfish Immunol. Lang Xie , Yixi Tao , Ronghua Wu , Qin Ye , Hao Xu , Yun Li	2019-12-01	-
28974511	TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia. Cancer Discov Riadh Lobbardi , Jordan Pinder , Barbara Martinez-Pastor , Marina Theodorou , Jessica S Blackburn , Brian J Abraham , Yuka Namiki , Marc Mansour , Nouran S Abdelfattah , Aleksey Molodtsov , Gabriela Alexe , Debra Toiber , Manon de Waard , Esha Jain , Myriam Boukhali , Mattia Lion , Deepak Bhere , Khalid Shah , Alejandro Gutierrez , Kimberly Stegmaier , Lewis B Silverman , Ruslan I Sadreyev , John M Asara , Marjorie A Oettinger , Wilhelm Haas , A Thomas Look , Richard A Young , Raul Mostoslavsky , Graham Dellaire , David M Langenau	2017-11-01	-
25534026	Integrative view of Î±2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage-specific losses. Mol. Biol. Evol. Daniel Petit , Elin Teppa , Anne-Marie Mir , DorothÃ©e Vicogne , Christine Thisse , Bernard Thisse , Cyril Filloux , Anne Harduin-Lepers	2015-04-01	ST3GAL3, ST3GAL4, ST3GAL1, LOC103060957, ST3GAL2, ST3GAL6, LOC102686537, LOC102688818, st3gal1, barx2, kdm4aa, senp7b, adgrg7.2, abi3bpb, ipmka, rnf212b, rnf212, slc25a28, adgrg7.1, ankrd2, neurog3, ptprfa, tlx2, tlx1, ets1, cdon, spon2a, spon2b, neurog1, ndrg3a, ldb2a, ldb1a, fli1a, nkx2.5, nkx2.3, klhl41b, cfl1, maea, prom1a, eif4ebp3l, cpne1, aars, pif1, rpl5a, polr1a, kdm4ab, map4k5, loxl3b, dact2, pcdh15a, ptk2aa, eif4ebp2, hyi, st3gal3a, fgfrl1a, ergic3, prkg1a, rad54l, dynlrb1, st3gal5, nit2, tirap, med8, nkx1.2la, dpydb, rbm39a, got1, cfl1l, sf3b3, st3gal3b, rpl5b, jagn1b, st3gal2, st3gal8, jagn1a, atl3, chrac1, st3gal4, cog8, ptbp2a, morn4, dmbx1b, st3gal1, st3gal1l, ptcd3, tmem45a, st3gal7, zbtb11, cnnm2a, st3gal1l3, prom2, slc24a3, col8a1a, hydin, impg2a, flrt3, il34, wisp1a, atoh8
22982668	Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev. Biol. Maija K Garnaas , Claire C Cutting , Alison Meyers , Peter B Kelsey , James M Harris , Trista E North , Wolfram Goessling	2012-12-15	rargb, aldh1a2, fabp10a, tlx1, lft1, lft2, pitx2, tfa, shha, foxa3, myl7, rarga, bmp4, vmhc, smad1, bmp2b, smad4a, smad5, prox1a, raraa, spaw, myh6, slc20a1a, aldh8a1, rarab, slc12a3, nkx2.4b, hand2
22538478	Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency. Leukemia J S Blackburn , S Liu , D M Raiser , S A Martinez , H Feng , N D Meeker , J Gentry , D Neuberg , A T Look , S Ramaswamy , A Bernards , N S Trede , D M Langenau	2012-09-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19862821	Hematopoietic immortalizing function of the NKL-subclass homeobox gene TLX1. Genes Chromosomes Cancer Lynnsey A Zweier-Renn , Teresa S Hawley , Sandra Burkett , Ali Ramezani , Irene Riz , Rima L Adler , Dennis D Hickstein , Robert G Hawley	2010-02-01	tlx1, TLX1
19562753	Evolution of developmental regulation in the vertebrate FgfD subfamily. J Exp Zool B Mol Dev Evol Richard Jovelin , Yi-Lin Yan , Xinjun He , Julian Catchen , Angel Amores , Cristian Canestro , Hayato Yokoi , John H Postlethwait	2010-01-15	-
20112453	Conservation of gene linkage in dispersed vertebrate NK homeobox clusters. Dev. Genes Evol. Karl R Wotton , Frida K Weierud , JosÃ© L JuÃ¡rez-Morales , LÃºcia E Alvares , Susanne Dietrich , Katharine E Lewis	2009-10-01	tlx2, tlx1, tlx3b, msx1b, msx3, msx1a, msx2b, nkx2.7, nkx2.5, nkx2.3, nkx3.2, pnx, mb, nkx1.2la, nkx1.2lb, nkx6.1, nkx3.3, nkx3-1, hmx2, nkx6.3, lbx1a, nkx6.2, msx2a, hmx3a, lbx2, hmx4, lbx1b, hmx1
18541024	Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. BMC Evol. Biol. Karl R Wotton , Frida K Weierud , Susanne Dietrich , Katharine E Lewis	2008-01-01	kazald3, dok2, kcnip1a, loxl4, tlx2, adra2b, adra2da, tlx1, tlx3b, npm1a, fgf8a, ldb2a, ldb1a, prom1a, mgea5, aup1, fbxw11a, fgf18a, fgf24, pcgf1, prom1b, kcnip3b, slc2a15a, dok1b, poll, fbxw11b, fgf17, kcnip1b, fgf18b, npm3, slc2a15b, add3b, npm1b, add1, npm2b, slit1a, prom2, add3a, dok1a, slc2a11a, slit1b, lbx1a, loxl2a, kazald2, add2, fbxw4, lbx2, fgf8b, dpcd, loxl2b, lbx1b, npm2a, slit2, slit3

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