Type | Description |
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Definition | ncRNA |
Date | Results | Publications |
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2020-04-25 11:56:00 | Findings show that the timing of sexually dimorphic differentiation of postmitotic, sex-shared neurons in the nervous system of the Caenorhabditis elegans male is controlled by the temporally regulated miRNA let-7 and its target protein lin-41 (lin-41). | 30599092 |
2020-02-29 10:16:00 | These studies reveal roles for a Makorin and a lncRNA in timing of sexual differentiation; moreover, they demonstrate deep conservation of the lin-28-let-7 system in controlling the functional maturation of the nervous system. | 31264582 |
2020-02-29 10:05:00 | These results identify let-7-LIN41 as a versatile regulatory module and reveal how several levels of post-transcriptional regulation promote transition into adulthood through controlling transcriptional programs. | 30910805 |
2020-01-04 11:02:00 | C. elegans let-7 primary transcript trans-splicing developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity | 30770392 |
2019-07-27 12:56:00 | sing the let-7 miRNA family in Caenorhabditis elegans, we find that seed match imperfections can increase specificity by requiring extensive pairing outside the miRNA seed region for efficient silencing and that such specificity is needed for faithful worm development. | 29897601 |
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