| Type | Description |
|---|---|
| Definition | DAB1, reelin adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 12:01:00 | In intestine a truncated Dab1 variant transmits the reelin signal and may play a role in clathrin-mediated apical endocytosis and in the control of cell-to-cell junction assembly. Dab1 variant may be a nucleocytoplasmic shuttling protein, inferred from its sequence and nuclear location. | 29470947 |
| 2018-03-31 10:12:00 | Melatonin ameliorated the neurotoxiciy and astrocyte activation induced by Abeta1-42 in the cerebral cortex. Melatonin also blocked the reduction in Reelin and Dab1 expression induced by Abeta1-42. Using in vitro study, Reelin inactivation completely abolished the protective effect of melatonin against Abeta1-42-induced neurotoxicity. | 28385118 |
| 2018-03-24 11:12:00 | These results indicated that Dab1 mediated Ang II-induced podocyte apoptosis via p38 signaling pathway. | 28676854 |
| 2010-06-14 11:28:00 | investigation of reelin-Disabled-1 signalling system in intestinal mucosa; Disabled-1 & VldlR protein signals were detected in the crypt and villus cells; they were particularly abundant in the terminal web domain of the enterocytes | 19946030 |
| 2010-01-21 00:00:00 | Dab1 binds to PI3 kinase in response to Reelin signaling and is required for normal cortical lamination | 12882964 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DAB1_RAT
UniprotKB:
Q8CJH2
UniParc:
UPI00000E8B4D
EMBL:
AB072426
Ensembl:
ENSRNOG00000007410
KO:
rno:266729
|
| Nucleutide sequences |
EMBL-CDS:
BAC20288.1
Ensembl_TRS:
ENSRNOT00000009977
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000009977
RefSeq:
XP_017448669.1,
XP_017448668.1,
XP_017448665.1,
NP_705885.1,
XP_008762076.1,
XP_017448667.1,
XP_017448664.1,
XP_017448666.1,
XP_017448670.1,
XP_017448671.1,
XP_006238556.1
|
| Others |
UniRef100:
UniRef100_Q8CJH2
UniRef90:
UniRef90_P97318
UniRef50:
UniRef50_O75553
UniGene:
Rn.206534
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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