| Type | Description |
|---|---|
| Definition | growth differentiation factor 9 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | A variant of human growth differentiation factor-9 that improves oocyte developmental competence. | 32350111 |
| 2020-03-21 10:52:00 | It was observed a statistically significant difference in genotype distribution of BMP15:c.852C>T between group POI and controls (p < 0.001). TT and TC genotypes were more frequently observed in group POI.. Concerning GDF9, no association was found among the studied genetic variants and POI or high FSH groups | 31392662 |
| 2019-08-03 11:14:00 | Here, the Targeted massively parallel sequencing identified the first homozygous 1-bp deletion variant in GDF9. This finding reveals a novel inheritance pattern of pathogenic variant in GDF9 associated with primary ovarian insufficiency (POI), thus improving the genetic diagnosis of this disorder. | 29044499 |
| 2019-05-18 12:35:00 | GDF9 promoted follicle-stimulating hormone (FSH)-induced progesterone production and STAR expression. | 30851298 |
| 2019-03-09 12:44:00 | GDF9 + BMP15, but not separately, significantly induce AMH expression in vitro and in vivo. GDF9 + BMP15, through the PI3K/Akt and Smad2/3 pathways synergistically recruit the coactivator p300 on the AMH promoter region that promotes acetylation of H3K27ac, facilitating AMH expression. | 30060157 |
| Type | IDs |
|---|---|
| Synonymous | POF14 |
| Gene |
UniProtKB-ID:
GDF9_HUMAN,
B4DXG3_HUMAN
UniprotKB:
O60383,
B4DXG3
UniParc:
UPI000012B396,
UPI00017A812B
EMBL:
AC004500,
AK315973,
BC096229,
AK301962,
BC096230,
BC096228,
BC096231
Ensembl:
ENSG00000164404
KO:
hsa:2661
|
| Nucleutide sequences |
EMBL-CDS:
AAH96229.1,
AAH96230.1,
AAH96228.1,
AAC08450.1,
AAH96231.1,
BAH14344.1,
BAG63375.1
Ensembl_TRS:
ENST00000378673,
ENST00000621295,
ENST00000624492,
ENST00000296875,
ENST00000624495
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367942,
ENSP00000484339,
ENSP00000485037,
ENSP00000485231,
ENSP00000296875
RefSeq:
NP_005251.1,
XP_006714648.1,
XP_011541612.1,
NP_001275755.1,
XP_011541611.1,
NP_001275753.1,
XP_011541613.1,
NP_001275756.1,
XP_005272014.1,
XP_011541610.1,
NP_001275757.1,
NP_001275754.1
|
| Others |
UniRef100:
UniRef100_O60383
UniRef90:
UniRef90_O60383
UniRef50:
UniRef50_O60383
UniGene:
Hs.25022
CCDS:
CCDS4162.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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