| Type | Description |
|---|---|
| Definition | growth differentiation factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:55:00 | Arsenic suppresses GDF1 expression via downregulation of specificity protein 1. | 33360347 |
| 2021-01-16 15:58:00 | A founder truncating variant in GDF1 causes autosomal-recessive right isomerism and associated congenital heart defects in multiplex Arab kindreds. | 32144877 |
| 2020-03-14 12:53:00 | Nkx2.5 acts upstream of GDF1 and the genetic variants in GDF1 promoter may confer genetic susceptibility to sporadic CHD potentially by altering its expression. | 31171573 |
| 2017-11-04 11:35:00 | Rare inherited and de novo variants in 2,871 congenital heart disease probands identified GDF1, MYH6, and FLT4 as causative genes. | 28991257 |
| 2016-09-24 10:46:00 | Our results suggest that the GDF1 rs4808863 polymorphism contributes to an increased risk of fetal CHDs, especially the subtypes of AVSD, LVOTO and left-right laterality defects. | 26656983 |
| Type | IDs |
|---|---|
| Synonymous | CERS1, CHTD6, DORV, DTGA3, LAG1, LASS1, RAI, UOG1 |
| Gene |
UniProtKB-ID:
GDF1_HUMAN,
A0A024R7N8_HUMAN
UniprotKB:
P27539,
A0A024R7N8
UniParc:
UPI0000169571
EMBL:
AC003972,
CH471106,
M62302,
AC005197
Ensembl:
ENSG00000223802,
ENSG00000130283
KO:
hsa:2657
|
| Nucleutide sequences |
EMBL-CDS:
AAA58501.1,
AAB94786.1,
EAW84744.1,
EAW84743.1
Gene_ORFName:
hCG_2045882
Ensembl_TRS:
ENST00000247005,
ENST00000623927
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000247005,
ENSP00000485582
RefSeq:
NP_001483.3,
NP_001374367.1
|
| Others |
UniRef100:
UniRef100_P27539
UniRef90:
UniRef90_P27539
UniRef50:
UniRef50_P27539
UniGene:
Hs.412355
CCDS:
CCDS42526.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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