| Type | Description |
|---|---|
| Definition | hormonally upregulated Neu-associated kinase |
| Date | Results | Publications |
|---|---|---|
| 2016-01-02 10:43:00 | Hunk has a role in normal intestinal proliferation and homeostasis and, although it does not alter overall survival rates, activity of this kinase does impact on tumour initiation rates during the early stages in tumourigenesis in the small intestine. | 25881306 |
| 2013-07-13 13:16:00 | Hunk is a previously unrecognized link between the Akt and c-myc oncogenic pathway induced by loss of Pten | 23520049 |
| 2011-04-30 10:35:00 | Hunk is required for HER2/neu-induced mammary tumorigenesis | 21393859 |
| 2010-05-10 11:16:00 | Data show that HUNK reconstitution in basal breast cancer cell lines prevented protein phosphatase 2-A (PP2A from binding to CFL-1. | 20133759 |
| 2010-01-21 00:00:00 | Reconstitution experiments revealed that Hunk is sufficient to restore the metastatic potential of Hunk-deficient mammary tumor cells, as well as defects in migration and invasion, and does so in a manner that requires its kinase activity. | 19717424 |
| Type | IDs |
|---|---|
| Synonymous | Bstk1, Mak-v |
| Gene |
UniProtKB-ID:
HUNK_MOUSE
UniprotKB:
O88866
UniParc:
UPI0000029CCA
EMBL:
AF167987,
AF055919
Ensembl:
ENSMUSG00000053414
KO:
mmu:26559
|
| Nucleutide sequences |
EMBL-CDS:
AAC61489.1,
AAF35282.1
Ensembl_TRS:
ENSMUST00000065856
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068007
RefSeq:
NP_056570.1,
XP_011244432.1
|
| Others |
UniRef100:
UniRef100_O88866
UniRef90:
UniRef90_O88866
UniRef50:
UniRef50_P57058
UniGene:
Mm.125874
CCDS:
CCDS28315.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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