| Type | Description |
|---|---|
| Definition | homer scaffolding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:27:00 | Distinct and Overlapping Expression Patterns of the Homer Family of Scaffolding Proteins and Their Encoding Genes in Developing Murine Cephalic Tissues. | 32070057 |
| 2020-04-11 11:59:00 | Data indicate decreased bone density in homer scaffolding proteins (Homer2/3) double knockout (DKO) mice. | 31319381 |
| 2016-05-28 10:09:00 | impaired mTORC1-Homer-3 activity underlies PC susceptibility in Spinocerebellar ataxia type 1 and presents a promising therapeutic target | 26748090 |
| 2010-01-21 00:00:00 | Homer2 and Homer3 proteins interact specifically with amyloid precursor protein (APP) by inhibiting APP processing and reducing secretion of Abeta peptides. | 18387811 |
| 2010-01-21 00:00:00 | study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin | 18218901 |
| Type | IDs |
|---|---|
| Synonymous | AW146114 |
| Gene |
UniProtKB-ID:
HOME3_MOUSE
UniprotKB:
Q99JP6
UniParc:
UPI00004358EF,
UPI00001928A6
EMBL:
AF093261,
BC005773,
AC158553
Ensembl:
ENSMUSG00000003573
KO:
mmu:26558
|
| Nucleutide sequences |
EMBL-CDS:
AAH05773.1,
AAC71025.1
Ensembl_TRS:
ENSMUST00000003669,
ENSMUST00000110124,
ENSMUST00000140212
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105751,
ENSMUSP00000117033,
ENSMUSP00000003669
RefSeq:
XP_036009953.1,
XP_036009957.1,
NP_036114.2,
XP_006509743.1,
XP_030099448.1,
XP_030099447.1,
XP_036009955.1,
XP_006509742.1,
XP_030099449.1,
XP_036009956.1,
NP_001139625.1,
XP_036009954.1,
XP_006509744.1
|
| Others |
UniRef100:
UniRef100_Q99JP6
UniRef90:
UniRef90_Q99JP6
UniRef50:
UniRef50_Q99JP6
UniGene:
Mm.388127,
Mm.440659
CCDS:
CCDS52569.1,
CCDS22363.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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