| Type | Description |
|---|---|
| Definition | integrator complex subunit 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 11:36:00 | Downregulation of Wnt/beta-catenin signaling was observed during the activation period, and the impairment of beta-catenin degradation reversed the tumor suppressor effects of INTS6. | 29895194 |
| 2018-05-19 10:43:00 | the results of our study show that down-regulated INTS6 expression is associated with a poorer prognosis in hepatocellular carcinoma (HCC) patients. This newly identified INTS6/WIF-1 axis indicates the molecular mechanism of HCC and may represent a therapeutic target in HCC patients. | 28899352 |
| 2016-09-24 11:59:00 | DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer. | 25660097 |
| 2016-03-05 11:34:00 | Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p. | 25686840 |
| 2014-06-07 10:18:00 | In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites. | 23986477 |
| Type | IDs |
|---|---|
| Synonymous | DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2 |
| Gene |
UniProtKB-ID:
INT6_HUMAN,
A0A024RDU0_HUMAN,
B3KQH5_HUMAN
UniprotKB:
Q9UL03,
A0A024RDU0,
B3KQH5
UniParc:
UPI0000030C84,
UPI000015D967,
UPI00001E9104,
UPI00001FCDF5
EMBL:
AL833524,
AL354820,
BK005730,
BC013358,
BC018725,
AF141326,
AL117626,
AK128795,
AK096696,
AL137780,
AF097645,
CH471075,
AK074946,
BC032386,
BC039829
Ensembl:
ENSG00000102786
KO:
hsa:26512
|
| Nucleutide sequences |
EMBL-CDS:
CAB56020.1,
DAA05730.1,
AAD39481.1,
AAF03046.1,
AAH32386.1,
AAH39829.1,
AAH18725.1,
AAH13358.1,
EAX08876.1,
EAX08877.1,
BAG54738.1,
EAX08879.1,
EAX08874.1,
BAG52037.1,
BAG53352.1
Gene_ORFName:
hCG_29123,
hCG_29123
Ensembl_TRS:
ENST00000311234,
ENST00000442263,
ENST00000398119,
ENST00000497989
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310260,
ENSP00000411245,
ENSP00000381187,
ENSP00000419871
RefSeq:
NP_036273.1,
XP_016876029.1,
NP_001035026.1,
XP_011533343.1,
NP_001293020.1,
XP_011533342.1,
NP_001035027.1
|
| Others |
UniRef100:
UniRef100_Q9UL03
UniRef90:
UniRef90_Q9UL03
UniRef50:
UniRef50_Q9UL03
UniGene:
Hs.439440
CCDS:
CCDS41890.1,
CCDS9428.1,
CCDS45048.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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