| Type | Description |
|---|---|
| Definition | hes related family bHLH transcription factor with YRPW motif like |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:58:00 | Elevated HEYL expression is associated with metastatic colorectal cancer. | 31796022 |
| 2018-08-04 11:22:00 | HEYL rs784621 AA genotype is associated with poor response to therapy in Non-small Cell Lung Cancer. | 28766235 |
| 2017-12-09 12:16:00 | LSD1 directly associates with the promoter of the HEYL gene. | 27018646 |
| 2015-07-25 10:40:00 | repression of TGFbeta signaling by Notch acting through HEYL may promote initiation of breast cancer | 25217524 |
| 2011-07-30 11:05:00 | Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors. | 21454491 |
| Type | IDs |
|---|---|
| Synonymous | HESR3, HEY3, HRT3, bHLHb33 |
| Gene |
UniProtKB-ID:
HEYL_HUMAN
UniprotKB:
Q9NQ87
UniParc:
UPI000013E317
EMBL:
AJ272215,
AL035404,
AF311885,
BC006087
Ensembl:
ENSG00000163909
KO:
hsa:26508
|
| Nucleutide sequences |
EMBL-CDS:
CAB75716.1,
AAG31158.1,
AAH06087.1
Ensembl_TRS:
ENST00000372852
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361943
RefSeq:
NP_055386.2,
XP_005270802.1
|
| Others |
UniRef100:
UniRef100_Q9NQ87
UniRef90:
UniRef90_Q9NQ87
UniRef50:
UniRef50_Q9DBX7
UniGene:
Hs.472566
CCDS:
CCDS439.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31796022 |
BMC Cancer Sarah Weber , Sebastian E Koschade , Christopher M Hoffmann , Taronish D Dubash , Klara M Giessler , Sebastian M Dieter , Friederike Herbst , Hanno Glimm , Claudia R Ball |
2019-12-03 | - |
| 28766235 |
Ann. Surg. Oncol. Yangki Seok , Hyo-Gyoung Kang , Shin Yup Lee , Ji Yun Jeong , Jin Eun Choi , Deuk Kju Jung , Cheng Cheng Jin , Mi Jeong Hong , Sook Kyung Do , Won Kee Lee , Ji Young Park , Kyung Min Shin , Seung Soo Yoo , Jaehee Lee , Sukki Cho , Seung Ick Cha , Chang Ho Kim , Sanghoon Jheon , Eung Bae Lee , Jae Yong Park |
2017-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27018646 |
Stem Cells Kazumi Hirano , Masakazu Namihira |
2016-07-01 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 26068074 |
PLoS ONE Daniela Salat , Anja Winkler , Henning Urlaub , Manfred Gessler |
2015-01-01 |
FBXO45,
MYCBP2,
HEY1,
HEY2,
HEYL,
HES1,
SKP1
|
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 25217524 |
The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. Cancer Res. Liangfeng Han , Adam Diehl , Nguyen K Nguyen , Preethi Korangath , Weiwen Teo , Soonweng Cho , Scott Kominsky , David L Huso , Lionel Feigenbaum , Alan Rein , Pedram Argani , Goran Landberg , Manfred Gessler , Saraswati Sukumar |
2014-11-15 |
Heyl,
HEYL
|
| 23275563 |
Development and application of a DNA microarray-based yeast two-hybrid system. Nucleic Acids Res. Bernhard Suter , Jean-Fred Fontaine , Reha Yildirimman , Tamás Raskó , Martin H Schaefer , Axel Rasche , Pablo Porras , Blanca M Vázquez-Ãlvarez , Jenny Russ , Kirstin Rau , Raphaele Foulle , Martina Zenkner , Kathrin Saar , Ralf Herwig , Miguel A Andrade-Navarro , Erich E Wanker |
2013-02-01 |
OPTN,
STAM2,
EIF1B,
HMG20A,
BASP1,
UBAC1,
TRIM38,
UBE2E3,
RAI2,
ARID5A,
TRAFD1,
IMMT,
ILVBL,
DUSP10,
CHRNA7,
MRFAP1L1,
UHRF2,
FAM46B,
CLCN2,
ADD3,
CREM,
CRIP2,
CRK,
CRY2,
ZMAT2,
MAGEB6,
XAGE3,
ZFC3H1,
DHRSX,
ESRRA,
ETV4,
ATF5,
GGA2,
UHRF1BP1L,
ZDHHC17,
HEY2,
RBFOX2,
FTL,
HYPM,
ZNF451,
HEYL,
OSTF1,
NPHP3,
ZSCAN1,
MAGEB18,
RAPGEF1,
CDIP1,
HTT,
UBE2K,
HMGA1,
HOXC4,
HOXC11,
IGF2R,
KIF22,
LASP1,
LOXL1,
C2orf27B,
MAGEB2,
MBD1,
MIPEP,
ASNS,
MSX2,
NCAM1,
NME4,
OPCML,
OTX2,
TMX2,
EVL,
TDP2,
PIK3R1,
PPAT,
ERCC6L,
GOLPH3L,
DPPA4,
FAM46A,
RNF20,
PSMB7,
PSPH,
DHX37,
SEMA4G,
GATAD1,
PLEKHB1,
RPL4,
ATXN1,
RBM26,
MLST8,
TTC23,
UPF3A,
SLC4A2,
SLC6A13,
TACC1,
TCTA,
TSC1,
YWHAE,
SF1,
ZNF655,
KCTD15,
ZXDC,
EHMT1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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