| Type | Description |
|---|---|
| Definition | glucosaminyl (N-acetyl) transferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-06-11 11:26:00 | GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient. | 26768364 |
| 2016-06-04 10:18:00 | GCNT1 expression in prostate cancer positively correlates with cancer progression and prostate-specific antigen recurrence. | 26390303 |
| 2015-08-15 10:05:00 | Results show that ST3Gal1 uses GM130-GRASP65 and giantin, whereas C2GnT-L uses only giantin for Golgi targeting and defective giantin dimerization in PC-3 and DU145 prostate cancer cells causes fragmentation of the Golgi and prevents its targeting. | 25086069 |
| 2014-10-18 12:55:00 | NMIIA is the master regulator of Golgi fragmentation induced by heat shock or inhibition/depletion of HSP70/90 through interaction with gylosyltransferases. | 23990450 |
| 2014-08-09 12:26:00 | GCNT1 is over-expressed in prostate cancer and is associated with higher levels of core 2 O-sLe(x) in PSA, PAP and MUC1 proteins. | 24854630 |
| Type | IDs |
|---|---|
| Synonymous | C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2 |
| Gene |
UniProtKB-ID:
GCNT1_HUMAN,
Q86T81_HUMAN
UniprotKB:
Q02742,
Q86T81
UniParc:
UPI000013CF63,
UPI0000191103
EMBL:
BC074886,
CH471089,
L41415,
M97347,
AL832647,
BC109102,
BC109101,
AL161626,
BC074885
Ensembl:
ENSG00000187210
KO:
hsa:2650
|
| Nucleutide sequences |
EMBL-CDS:
AAH74886.1,
AAI09103.1,
AAA96661.1,
EAW62580.1,
AAA35919.1,
AAH74885.1,
AAI09102.1,
CAD89956.1
Ensembl_TRS:
ENST00000376730,
ENST00000444201,
ENST00000442371
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365920,
ENSP00000390703,
ENSP00000415454
RefSeq:
NP_001091102.1,
NP_001091103.1,
NP_001481.2,
NP_001091105.1,
NP_001091104.1
|
| Others |
UniRef100:
UniRef100_Q02742,
UniRef100_Q86T81
UniRef90:
UniRef90_Q02742
UniRef50:
UniRef50_Q02742
UniGene:
Hs.521568
CCDS:
CCDS6653.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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