| Type | Description |
|---|---|
| Definition | lysine acetyltransferase 2A |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | Elevated GCN5 expression confers tamoxifen resistance by upregulating AIB1 expression in ER-positive breast cancer. | 32987137 |
| 2021-03-13 13:17:00 | Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure. | 32820047 |
| 2020-10-24 14:13:00 | [Expression and Mechanism of KAT2A and CDK4/CDK6 in Children with Acute Leukemia]. | 33067952 |
| 2020-08-12 12:45:00 | GCN-5/PGC-1alpha signaling is activated and associated with metabolism in Cyclin E1-driven high grade serous ovarian cancer | 31313989 |
| 2020-07-04 10:44:00 | KAT2A is highly expressed in human pancreatic ductal adenocarcinoma (PDAC) specimens and positively correlated with advanced stages of PDAC and short patients' survival. KAT2A expression in PDAC specimens is correlated with 14-3-3zeta expression, and KAT2A regulates H3K79 succinylation in the promoter region of YWHAZ to promote YWHAZ mRNA and 14-3-3zeta expression, thereby preventing beta-catenin degradation. | 31610265 |
| Type | IDs |
|---|---|
| Synonymous | GCN5, GCN5L2, PCAF-b, hGCN5 |
| Gene |
UniProtKB-ID:
KAT2A_HUMAN
UniprotKB:
Q92830
UniParc:
UPI000000D978,
UPI000002AA52
EMBL:
BC032743,
BC105977,
U57316,
CH471152,
AF029777,
BC039907
Ensembl:
ENSG00000108773
KO:
hsa:2648
|
| Nucleutide sequences |
EMBL-CDS:
AAI05978.1,
AAH32743.1,
AAC39769.1,
EAW60803.1,
AAC50641.1,
AAH39907.1
Ensembl_TRS:
ENST00000225916
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225916
RefSeq:
XP_006721881.1,
NP_001363156.1,
XP_016879937.1,
NP_066564.2
|
| Others |
UniRef100:
UniRef100_Q92830
UniRef90:
UniRef90_Q92830
UniRef50:
UniRef50_Q92830
UniGene:
Hs.463045
CCDS:
CCDS11417.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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