| Type | Description |
|---|---|
| Definition | LIM homeobox 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:48:00 | LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons. | 31907793 |
| 2020-12-05 13:03:00 | Methylation-mediated silencing of the LIM homeobox 6 (LHX6) gene promotes cell proliferation in human pancreatic cancer. | 32248980 |
| 2019-11-02 13:25:00 | LHX6 gene expression is regulated by DNA methylation and can inhibit the proliferation, invasion and migration through Wnt/beta-catenin and P53 signaling pathways during the Microcystin-LR-induced hepatocarcinogenesis. | 31151060 |
| 2019-10-05 11:59:00 | The downregulation of LHX6 expression might be important in promoting cancer progression. [review] | 29533904 |
| 2019-10-05 11:24:00 | The orthotopic implantation model showed that miR-1290 overexpression promoted tumor growth while LHX6 overexpression inhibited it. MiR-1290 could promote glioma cell propagation and metastasis by inhibiting LHX6. | 29226322 |
| Type | IDs |
|---|---|
| Synonymous | LHX6.1 |
| Gene |
UniProtKB-ID:
LHX6_HUMAN,
A0A024R852_HUMAN
UniprotKB:
Q9UPM6,
A0A024R852
UniParc:
UPI0000F58F26,
UPI0001914DB9,
UPI000013C83A,
UPI00020EE5BD,
UPI0000E0BF7D,
UPI0000140088
EMBL:
AK289827,
BC103937,
CH471090,
AK297175,
AL162424,
AK313808,
BC103936,
AL136570,
AK299709,
AB031041,
AK126982,
AB031042
Ensembl:
ENSG00000106852
KO:
hsa:26468
|
| Nucleutide sequences |
EMBL-CDS:
CAB66505.1,
AAI03938.1,
BAG36544.1,
EAW87516.1,
BAH13108.1,
AAI03937.1,
BAA83423.1,
BAF82516.1,
BAA83422.1,
EAW87515.1,
BAH12516.1,
EAW87517.1
Gene_ORFName:
hCG_28360
Ensembl_TRS:
ENST00000394319,
ENST00000340587,
ENST00000559895,
ENST00000373754,
ENST00000373755,
ENST00000541397
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000475927,
ENSP00000362860,
ENSP00000441464,
ENSP00000340137,
ENSP00000377854,
ENSP00000362859
RefSeq:
NP_055183.2,
NP_954629.2,
XP_011516823.1,
NP_001229263.1,
XP_005251973.1,
NP_001229262.1,
NP_001335119.1,
XP_011516824.1,
NP_001229264.1
|
| Others |
UniRef100:
UniRef100_Q9UPM6
UniRef90:
UniRef90_Q9UPM6
UniRef50:
UniRef50_Q9UPM6
UniGene:
Hs.103137
CCDS:
CCDS6837.2,
CCDS56583.1,
CCDS6838.2,
CCDS59144.1,
CCDS87683.1,
CCDS56584.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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