| Type | Description |
|---|---|
| Definition | polymerase (DNA directed), iota |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 11:16:00 | Pol iota occasionally accesses the replication fork to generate a first mutation, and Pol zeta extends the mismatch with a second mutation. | 27455952 |
| 2017-08-12 10:14:00 | Mouse DNA polymerase iota lacking exon 2 (42 amino acids) is catalytically inactive in vitro. | 28077247 |
| 2017-08-12 10:14:00 | Exon 2 deletion abrogates both the DNA polymerase and dRP lyase activities of Pol iota in the presence of either Mg(2+) or Mn(2+) ions. Thus, 129-derived strains of mice express catalytically inactive alternatively spliced Pol iota variant. | 28077248 |
| 2016-02-13 12:26:00 | PolH contributes to accurate translesion synthesis (TLS) past both T- & C-containing dimers. PolI is involved in error-prone TLS past cytosine-containing dimers when Poleta is inactivated. | 25733082 |
| 2014-09-06 12:23:00 | Poliota causes the Par2 effect and inhibits tumorigenesis and mutagenesis | 23955086 |
| Type | IDs |
|---|---|
| Synonymous | Rad30b |
| Gene |
UniProtKB-ID:
POLI_MOUSE,
E9Q3H9_MOUSE,
A0A0R4J1Z5_MOUSE,
E9QJU6_MOUSE
UniprotKB:
Q6R3M4,
E9Q3H9,
A0A0R4J1Z5,
E9QJU6
UniParc:
UPI000043A9A0,
UPI0001611667,
UPI00004C8012,
UPI0001DD34F2,
UPI0000351979
EMBL:
AF151691,
AY515317,
AY515316,
HQ698887,
BC082278,
AC134831
Ensembl:
ENSMUSG00000038425
KO:
mmu:26447
|
| Nucleutide sequences |
EMBL-CDS:
AAH82278.1,
AAS75834.1,
AAS75835.1,
AAD50424.1,
AEQ34092.1
Ensembl_TRS:
ENSMUST00000159389,
ENSMUST00000161542,
ENSMUST00000043286,
ENSMUST00000121674
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000123964,
ENSMUSP00000039869,
ENSMUSP00000124877,
ENSMUSP00000112563
RefSeq:
NP_036102.2,
XP_006526008.1,
XP_030106327.1,
XP_006526009.1,
NP_001276444.1,
XP_017173399.1,
XP_011245236.1,
XP_036017052.1,
NP_001276445.1,
XP_030106325.1,
NP_001129562.1,
XP_011245235.1,
XP_036017053.1
|
| Others |
UniRef100:
UniRef100_Q6R3M4,
UniRef100_E9Q3H9,
UniRef100_E9QJU6
UniRef90:
UniRef90_Q6R3M4
UniRef50:
UniRef50_Q9UNA4
UniGene:
Mm.244352
CCDS:
CCDS50317.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员