| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 5, group A, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:11:00 | Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination. | 30872705 |
| 2020-07-04 10:22:00 | The expression level of Notch2 was significantly reduced in Nr5a1 transgenic mice, and the ovarian phenotype was almost completely rescued by in utero treatment with a NOTCH2 agonist. Suppression of Nr5a1 during the fetal period optimizes ovarian development by fine-tuning Notch signaling. | 30877223 |
| 2019-09-28 10:03:00 | Study data indicates that insulin regulates adrenal steroidogenesis by up regulating the transcriptional activity of SF-1 both in vitro and in vivo. Overexpression of FoxO1, a downstream transcription factor regulated by insulin, inhibits the expression and transcriptional activity of SF-1 suggesting that insulin might increase the activity of SF-1 by phosphorylating and inactivating FoxO1. | 29567944 |
| 2018-09-01 10:54:00 | ChIP-sequence/ChIP studies indicated that Ad4BP/SF-1 binds to the upstream region of Ccne1 (cyclin E1) gene during G1/S phase. | 28325912 |
| 2017-12-16 11:31:00 | Collectively, this evidence suggests that SF-1 expression in ventromedial hypothalamic nucleus neurons is required for the beneficial effects of exercise on metabolism. | 27874828 |
| Type | IDs |
|---|---|
| Synonymous | Ad4BP, ELP, ELP-3, Ftz-F1, Ftzf1, SF-1, SF1, STF-1 |
| Gene |
UniProtKB-ID:
STF1_MOUSE
UniprotKB:
P33242
UniParc:
UPI000217CB69,
UPI0000001716
EMBL:
S65919,
D10584,
AK144376,
AK134378,
AF511594,
S65878,
BC110477,
S65875,
BC110476,
AL844842,
S65877,
S65876
Ensembl:
ENSMUSG00000026751
KO:
mmu:26423
|
| Nucleutide sequences |
EMBL-CDS:
AAI10478.1,
BAE22121.1,
BAA01441.1,
AAI10477.1,
AAB28339.1,
BAE25855.1,
AAM43952.1,
AAB28338.1
Ensembl_TRS:
ENSMUST00000112883,
ENSMUST00000028084
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108504,
ENSMUSP00000028084
RefSeq:
NP_620639.1,
NP_001303616.1
|
| Others |
UniRef100:
UniRef100_P33242
UniRef90:
UniRef90_P33242
UniRef50:
UniRef50_Q13285
UniGene:
Mm.31387
CCDS:
CCDS16011.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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