| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 10:58:00 | MAP3K4 activity controls epithelial-to-mesenchymal transition through the ubiquitination and degradation of HDAC6. | 28273454 |
| 2017-05-13 17:19:00 | by forming a complex with MEKK4 in skeletal muscle fibers, Gadd45a increases MEKK4 protein kinase activity, which is both sufficient to induce skeletal muscle fiber atrophy and required for Gadd45a-mediated skeletal muscle fiber atrophy. | 27358404 |
| 2015-01-17 12:34:00 | Map3k4 haploinsufficiency is the cause of T-associated sex reversal. | 24452333 |
| 2013-02-02 11:22:00 | suggest a requirement for GADD45gamma in promoting MAP3K4-mediated activation of p38 MAPK signaling in embryonic gonadal somatic cells for testis determination | 23102580 |
| 2011-10-08 10:14:00 | regulates epithelial-mesenchymal transition in trophoblast stem cells | 21549327 |
| Type | IDs |
|---|---|
| Synonymous | D17Rp17, D17Rp17e, MAPKKK4, MEKK 4, MTK1, Mek4b, Mekk4, RP17, Rp17a, Tas, mKIAA0213 |
| Gene |
UniProtKB-ID:
M3K4_MOUSE
UniprotKB:
O08648
UniParc:
UPI00001D6F7C,
UPI000047493F
EMBL:
BC058719,
U85608,
U66240,
U85607
Ensembl:
ENSMUSG00000014426
KO:
mmu:26407
|
| Nucleutide sequences |
EMBL-CDS:
AAH58719.1,
AAC08286.1,
AAC53127.1,
AAC53126.1
Ensembl_TRS:
ENSMUST00000089058,
ENSMUST00000233755
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000086459,
ENSMUSP00000156730
RefSeq:
XP_030105680.1,
NP_036078.2,
XP_030105679.1,
NP_001344651.1,
XP_036016515.1
|
| Others |
UniRef100:
UniRef100_O08648
UniRef90:
UniRef90_O08648
UniRef50:
UniRef50_Q9Y6R4
UniGene:
Mm.28587
CCDS:
CCDS88991.1,
CCDS37435.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员