| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 12:20:00 | results suggest that MEKK3 plays important roles in platelet MAPK activation | 29941457 |
| 2019-04-13 10:05:00 | The expression of MEKK3 in the midbrain is regulated by microRNA-124 in an experimental model of Parkinson's disease. | 29329581 |
| 2017-10-14 11:38:00 | MiR-188 regulated MAP3K3 expression in bone marrow cells.MAP3K3 is involved in miR-188-induced promotion of bone marrow cells senescence. | 28640956 |
| 2017-07-01 12:19:00 | this study shows that TAK1 negatively regulates lipopolysaccharide-induced cytokine secretion in myeloid cells by inhibiting MEKK3 activities | 27671672 |
| 2016-05-14 11:25:00 | endothelial-specific loss of Mekk3, Klf2 or Klf4 markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality | 27027284 |
| Type | IDs |
|---|---|
| Synonymous | AW548911, MAPKKK3, Mekk3, mKIAA4031 |
| Gene |
UniProtKB-ID:
M3K3_MOUSE
UniprotKB:
Q61084
UniParc:
UPI00000019C9
EMBL:
BC023781,
U43187
Ensembl:
ENSMUSG00000020700
KO:
mmu:26406
|
| Nucleutide sequences |
EMBL-CDS:
AAH23781.1,
AAB03535.1
Ensembl_TRS:
ENSMUST00000002044
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002044
RefSeq:
XP_036012604.1,
XP_036012603.1,
NP_036077.1,
XP_011247339.1
|
| Others |
UniRef100:
UniRef100_Q61084
UniRef90:
UniRef90_Q61084
UniRef50:
UniRef50_Q99759
UniGene:
Mm.27041
CCDS:
CCDS25548.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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