| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:28:00 | Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia. | 31219577 |
| 2019-12-14 11:43:00 | These results suggest that MKK4 and MKK7 may serve redundant and unique roles in molecular signaling important for retinal development and injury response following axonal insult. | 30367030 |
| 2019-02-23 13:33:00 | we generated neuron-specific Mkk7 knockout mice (MKK7 cKO), which impaired constitutive activation of JNK in the nervous system. MKK7 cKO mice displayed impaired circadian behavioral rhythms and decreased locomotor activity. MKK7 cKO mice at 8 months showed motor dysfunctions such as weakness of hind-limb and gait abnormality in an age-dependent manner. | 28779160 |
| 2019-01-12 10:08:00 | SENP3 potentiates lipopolysaccharide-induced TLR4 signaling via deSUMOylation of MKK7 leading to enhancement in JNK phosphorylation and the downstream events | 29352108 |
| 2017-10-21 12:52:00 | High Map2k7 expression is associated with T-cell acute lymphoblastic leukemia. | 27872496 |
| Type | IDs |
|---|---|
| Synonymous | 5930412N11Rik, JNKK 2, Jnkk2, MAPKK 7, MEK 7, Mapkk7, Mek7, Mkk7, Prkmk7, sek2 |
| Gene |
UniProtKB-ID:
MP2K7_MOUSE
UniprotKB:
Q8CE90
UniParc:
UPI0000020CC1,
UPI0000E6A795,
UPI0000E6A796,
UPI00000E818C,
UPI00000E7FEC,
UPI00000E9162,
UPI00000E72EA,
UPI00000E5C64
EMBL:
AF060945,
BC070467,
AK031137,
U74464,
U93030,
U74463,
AF060947,
AF022113,
AF026216,
AB005654,
AF022112,
AF060943,
AK165184,
AK028772,
U93031,
AF060944,
AF060946
Ensembl:
ENSMUSG00000109061,
ENSMUSG00000002948
KO:
mmu:26400
|
| Nucleutide sequences |
EMBL-CDS:
AAB63447.1,
AAD15821.1,
AAC16275.1,
AAB81848.1,
BAE38066.1,
AAD15822.1,
BAC27272.1,
BAC26111.1,
BAA24383.1,
AAH70467.1,
AAD15819.1,
AAC53365.1,
AAC53364.1,
AAD15823.1,
AAB63448.1,
AAD15820.1,
AAC16274.1
Ensembl_TRS:
ENSMUST00000110995,
ENSMUST00000062686,
ENSMUST00000110998,
ENSMUST00000145165,
ENSMUST00000003027,
ENSMUST00000110996,
ENSMUST00000110999,
ENSMUST00000110994
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003027,
ENSMUSP00000106624,
ENSMUSP00000106627,
ENSMUSP00000106626,
ENSMUSP00000054512,
ENSMUSP00000106622,
ENSMUSP00000117418,
ENSMUSP00000106623
RefSeq:
NP_001157644.1,
NP_036074.2,
NP_001278707.1,
NP_001036022.1,
NP_001278712.1,
NP_001278706.1
|
| Others |
UniRef100:
UniRef100_Q8CE90
UniRef90:
UniRef90_Q8CE90
UniRef50:
UniRef50_O14733
UniGene:
Mm.3906
CCDS:
CCDS80854.1,
CCDS40209.1,
CCDS40208.1,
CCDS80852.1,
CCDS80853.1,
CCDS52474.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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