| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling. | 32371393 |
| 2021-01-02 12:49:00 | Circ_016719 plays a critical role in neuron cell apoptosis induced by I/R via targeting miR-29c/Map2k6. | 31698040 |
| 2018-02-10 11:24:00 | acts as a repressor of UCP1 expression, suggesting that its inhibition promotes adipose tissue browning and increases organismal energy expenditure | 29021624 |
| 2017-11-04 11:56:00 | MAP2K6 functions in mouse testis determination, via positive effects on Sry, and a minor role for MAP2K3. | 27009039 |
| 2014-09-13 10:08:00 | MKK3 and MKK6 differentially regulate bone loss due to estrogen withdrawal. MKK3 directly mediates osteoclastogenesis while MKK6 likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation. | 24400116 |
| Type | IDs |
|---|---|
| Synonymous | MAPKK 6, MAPKK6, MEK6, MKK6, Prkmk6, SAPKK3 |
| Gene |
UniProtKB-ID:
MP2K6_MOUSE,
Q543Z5_MOUSE
UniprotKB:
P70236,
Q543Z5
UniParc:
UPI000000404D
EMBL:
AK141708,
X97052,
AK162671,
BC075652,
AK043482
Ensembl:
ENSMUSG00000020623
KO:
mmu:26399
|
| Nucleutide sequences |
EMBL-CDS:
CAA65764.1,
AAH75652.1,
BAE37014.1,
BAC31556.1,
BAE24808.1
Ensembl_TRS:
ENSMUST00000020949
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020949
RefSeq:
NP_001343281.1,
NP_001343276.1,
XP_011247337.1,
NP_001343274.1,
NP_001343275.1,
XP_036012602.1,
NP_036073.1,
XP_036012601.1,
XP_011247336.2,
NP_001343282.1
|
| Others |
UniRef100:
UniRef100_P70236
UniRef90:
UniRef90_P70236
UniRef50:
UniRef50_P70236
UniGene:
Mm.14487
CCDS:
CCDS25592.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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