| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:12:00 | By regulating the TGFbeta1/TAK1/MMK3/p38MAPK signaling pathway. | 31545406 |
| 2017-12-30 12:34:00 | The study identifies MKK3 as a negative regulator of mitochondrial function and inflammatory responses to cigarette smoke. | 27717867 |
| 2017-11-04 11:56:00 | MAP2K6 functions in mouse testis determination, via positive effects on Sry, and a minor role for MAP2K3. | 27009039 |
| 2017-08-19 10:26:00 | ATF3 upregulation in cardiac fibroblasts in response to hypertensive stimuli protects the heart by suppressing Map2K3 expression and subsequent p38-transforming growth factor-beta signaling. | 28249877 |
| 2016-10-29 10:47:00 | miR-21 targets MKK3 in vivo and in vitro, inhibiting the downstream factors IL-6 and TNF-alpha, in ischemia pretreatment protection from ischemia-reperfusion induced kidney injury. | 26149640 |
| Type | IDs |
|---|---|
| Synonymous | AW212142, MAPKK 3, MEK3, MKK3, MKK3b, Prkmk3 |
| Gene |
UniProtKB-ID:
MP2K3_MOUSE,
Q5SWN9_MOUSE
UniprotKB:
O09110,
Q5SWN9
UniParc:
UPI000002AE43,
UPI000002791E
EMBL:
X93150,
D87115,
AK011002,
AK166507,
AK167209,
AK008141,
BC007467,
AK168710
Ensembl:
ENSMUSG00000018932
KO:
mmu:26397
|
| Nucleutide sequences |
EMBL-CDS:
AAH07467.1,
BAA13247.1,
BAB27321.1,
CAA63649.1,
BAB25489.1,
BAE38817.1,
BAE40552.1,
BAE39336.1
Ensembl_TRS:
ENSMUST00000019076
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019076
RefSeq:
NP_032954.1
|
| Others |
UniRef100:
UniRef100_O09110
UniRef90:
UniRef90_O09110
UniRef50:
UniRef50_O09110
UniGene:
Mm.18494
CCDS:
CCDS24804.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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