| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice. | 32800341 |
| 2020-01-11 10:44:00 | Our findings demonstrate a novel regulatory function for MEK2 in response to TLR4 activation in IL-1beta production through modulating HIF-1alpha expression. | 30710049 |
| 2017-12-30 13:02:00 | data suggest that, although short-term suppression of Mek1/2 in ES cells helps to maintain an inner cell mass-like epigenetic state, prolonged suppression results in irreversible changes that compromise their developmental potential | 28746311 |
| 2017-12-02 10:07:00 | Erk5 MAP kinase is activated in response to PDGF-BB in the smooth muscle cell line MOVAS in a manner dependent on Mekk2, Mek1/2, Mek5, PI3-kinase and protein kinase C | 27339033 |
| 2017-09-02 12:37:00 | fluid shear stress induces autocrine TGF-beta/ALK5-induced target gene expression in renal epithelial cells, which is partially restrained by MEK1/2-mediated signaling. | 28168444 |
| Type | IDs |
|---|---|
| Synonymous | AA589381, MEK2, MK2, Prkmk2 |
| Gene |
UniProtKB-ID:
MP2K2_MOUSE,
Q8CB46_MOUSE,
Q91YS7_MOUSE
UniprotKB:
Q63932,
Q8CB46,
Q91YS7
UniParc:
UPI00000E6A8B,
UPI00000E953D,
UPI00000E88EB
EMBL:
BC014830,
AK171584,
CH466553,
AK036822,
AK080574,
AK009392,
AK172055,
AC155932,
S68267
Ensembl:
ENSMUSG00000035027
KO:
mmu:26396
|
| Nucleutide sequences |
EMBL-CDS:
BAB26261.1,
EDL31456.1,
BAC37945.1,
AAC60678.1,
BAC29592.1,
AAH14830.1,
BAE42803.1,
BAE42542.1
Ensembl_TRS:
ENSMUST00000143517,
ENSMUST00000105331
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000121111,
ENSMUSP00000100968
RefSeq:
XP_006513746.1,
NP_075627.2,
NP_001334073.1,
NP_001345468.1
|
| Others |
UniRef100:
UniRef100_Q91YS7,
UniRef100_Q63932
UniRef90:
UniRef90_Q63932,
UniRef90_A0A250YHA8
UniRef50:
UniRef50_Q63932,
UniRef50_P36506
UniGene:
Mm.275436
CCDS:
CCDS24044.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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