| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Constitutive activation of mitogen-activated protein kinase kinase (MEK1) in ileal enterocytes leads to dysplasia and a predisposition to cancer. | 33470189 |
| 2020-10-24 13:59:00 | MEK1 regulates pulmonary macrophage inflammatory responses and resolution of acute lung injury. | 31801908 |
| 2020-09-19 16:30:00 | ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity. | 30964448 |
| 2018-10-13 10:50:00 | he Mek1(Y130C) mutation recapitulates major aspects of cardio-facio-cutaneous syndrome. | 29590634 |
| 2018-02-17 11:37:00 | MEK1 does not act as a general tumor suppressor in leukemogenesis. Rather, its effects strongly depend on the genetic context (RAS versus MYC-driven leukemia) and on the cell type involved. | 27741509 |
| Type | IDs |
|---|---|
| Synonymous | MAPKK1, MEKK1, Mek1, Prkmk1 |
| Gene |
UniProtKB-ID:
MP2K1_MOUSE,
Q3TMJ8_MOUSE
UniprotKB:
P31938,
Q3TMJ8
UniParc:
UPI0000020E56
EMBL:
AY902345,
BC054754,
AK165894,
AK146931,
AK167336,
L02526
Ensembl:
ENSMUSG00000004936
KO:
mmu:26395
|
| Nucleutide sequences |
EMBL-CDS:
AAA39523.1,
AAH54754.1,
BAE27542.1,
AAY21055.1,
BAE38443.1,
BAE39437.1
Ensembl_TRS:
ENSMUST00000005066
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005066
RefSeq:
NP_032953.1,
XP_006511259.1
|
| Others |
UniRef100:
UniRef100_P31938
UniRef90:
UniRef90_Q01986
UniRef50:
UniRef50_Q02750-2
UniGene:
Mm.248907
CCDS:
CCDS23277.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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