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26388 Ifi202b

26388

Ifi202b

interferon activated gene 202B

protein-coding

Mus musculus

基因描述

Type Description
Definition interferon activated gene 202B

研究结论

Date Results Publications
2019-06-08 13:21:00 Enforced expression of IFI16-b inhibits the activation of AIM2 inflammasome, whereas knockdown of IFI16-b augments interleukin-1b secretion triggered by dsDNA but not dsRNA Thus, cytoplasm-localized IFI16-b is functionally equivalent to mouse p202 that exerts an inhibitory effect on AIM2 inflammasome. . 30104205
2019-03-16 12:05:00 p202 promotes osteogenesis in mouse bone marrow stromal cells. 29853536
2019-02-02 12:33:00 Ifi202b and IFI16 have roles as obesity genes 29478099
2018-12-22 10:03:00 the expression level of Ifi202b showed the most sex difference in correlation with known immune-related genes 30246031
2014-08-30 11:16:00 These results, together with the reported data on p202 HINb, lead to an interaction model for full-length p202 and dsDNA which provides a conceivable mechanism for the negative regulation of Aim2 inflammasome activation by p202. 24419611

名称对应

Type IDs
Synonymous Ifbip-1, Ifi202, Ifi202a, p202
Gene
UniProtKB-ID: IFI2_MOUSE
UniprotKB: Q9R002
UniParc: UPI00001927FD
EMBL: AC170584, BC055888, BC018233, M31418, AF140672, DQ222946
Ensembl: ENSMUSG00000026535
KO: mmu:26388
Nucleutide sequences
EMBL-CDS: AAH18233.1, AAH55888.1, AAF04260.1, AAA39312.1, ABB00055.1
Ensembl_TRS: ENSMUST00000000266
Protein sequencees
Ensembl_PRO: ENSMUSP00000000266
RefSeq: NP_036070.2, NP_032353.2
Others
UniRef100: UniRef100_Q9R002
UniRef90: UniRef90_Q9R002
UniRef50: UniRef50_Q9R002
UniGene: Mm.218770
CCDS: CCDS35794.1

全选

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研究热度

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