| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization. | 32486261 |
| 2019-09-14 10:07:00 | These data indicate that GRK2, GRK5 and GRK6 redundantly modulate Smo-GATA crosstalk in fetal mouse hearts, orchestrating transcriptional pathways previously linked to clinical and experimental atrioventricular canal defects | 29969579 |
| 2019-05-04 10:06:00 | findings show that chemerin-activated CMKLR1 regulation in inflammatory macrophages is largely GRK6 and beta-arrestin mediated, which may impact innate immunity and have therapeutic implications in rheumatic disease. | 30576947 |
| 2018-08-04 10:51:00 | Conditions for optimal dendritic cells guidance are perfectly provided by the CCL21 gradients measured in vivo. Furthermore, CCR7 signal termination by the G-protein-coupled receptor kinase 6 (GRK6) is crucial for haptotactic but dispensable for chemotactic CCL21 gradient sensing in vitro and confirm those observations in vivo. | 28457871 |
| 2018-06-23 10:42:00 | These studies suggest a previously unrecognized and novel role for GRK6 in neutrophil migration specific to pulmonary tissue during bacterial infection. | 28939643 |
| Type | IDs |
|---|---|
| Synonymous | Gprk6 |
| Gene |
UniProtKB-ID:
GRK6_MOUSE,
A0A286YDA5_MOUSE,
A0A286YE10_MOUSE,
Q9EP84_MOUSE,
A0A286YDZ5_MOUSE
UniprotKB:
O70293,
A0A286YDA5,
A0A286YE10,
Q9EP84,
A0A286YDZ5
UniParc:
UPI0000027C2B,
UPI0003BC01EE,
UPI0003BBBA34,
UPI00000E7D25,
UPI0003BBDEBB,
UPI000002AACA
EMBL:
AF040749,
CT009762,
AF040748,
Y15798,
AF040747,
Y17967,
AF040754,
Y15797,
Y15799,
BC075719
Ensembl:
ENSMUSG00000074886
KO:
mmu:26385
|
| Nucleutide sequences |
EMBL-CDS:
AAC09270.1,
AAC09268.1,
AAC09265.1,
CAA76976.1,
CAA75790.1,
CAA75789.1,
AAC09269.1,
CAA76975.1,
AAH75719.1,
CAA75788.1,
CAA76974.1
Ensembl_TRS:
ENSMUST00000001115,
ENSMUST00000224118,
ENSMUST00000224995,
ENSMUST00000225925,
ENSMUST00000099482,
ENSMUST00000224653
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000152968,
ENSMUSP00000001115,
ENSMUSP00000153344,
ENSMUSP00000153668,
ENSMUSP00000097081,
ENSMUSP00000153623
RefSeq:
NP_001364005.1,
NP_001272992.1,
NP_001106182.1,
NP_036068.2,
NP_001272994.1,
NP_001272993.1,
NP_001364006.1,
NP_001033107.1,
NP_001272995.1
|
| Others |
UniRef100:
UniRef100_A0A286YDA5,
UniRef100_O70293,
UniRef100_O70293-2,
UniRef100_A0A286YE10
UniRef90:
UniRef90_Q3UK88,
UniRef90_O70293,
UniRef90_Q3TTW2
UniRef50:
UniRef50_O70293,
UniRef50_P32298-2,
UniRef50_G3WK26
UniGene:
Mm.10193
CCDS:
CCDS88457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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