| Type | Description |
|---|---|
| Definition | estrogen related receptor, alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 10:20:00 | Transcriptome and ChIP-seq analyses and found that many genes that were co-regulated by both THRB1 and ESRRA were involved in mitochondrial metabolic pathways. | 29945885 |
| 2019-04-20 10:52:00 | These findings support the therapeutic application of resveratrol and ERR-alpha in combating obesity-mediated cardiac dysfunction. | 30342030 |
| 2019-03-02 12:07:00 | results reveal a novel ERRalpha/RANK axis by which ERRalpha in primary breast cancer promotes early dissemination of cancer cells to bone. These findings suggest that ERRalpha may be a useful therapeutic target to prevent bone metastases. | 30478447 |
| 2019-03-02 10:24:00 | this study identifies ESRRA as a critical activator of autophagy via both transcriptional and posttranslational control to promote antimicrobial host responses. | 28841353 |
| 2019-01-19 11:14:00 | Systemic ablation of ERRalpha in mice demonstrated clear beneficial effects for loss of ERRalpha function in protection from HFD-provoked body weight gain manifested not only from a reduction in white adipose tissue stores but also from an impediment in intrahepatic lipid accumulation. The prevention of HFD-induced NAFLD in ERRalpha-null mice was underscored by transcriptional repression of de novo lipogenesis. | 29635284 |
| Type | IDs |
|---|---|
| Synonymous | ERRalpha, Err1, Estrra, Nr3b1 |
| Gene |
UniProtKB-ID:
ERR1_MOUSE
UniprotKB:
O08580
UniParc:
UPI00001C61D5
EMBL:
BC138586,
U85259,
BC171958,
AK156371
Ensembl:
ENSMUSG00000024955
KO:
mmu:26379
|
| Nucleutide sequences |
EMBL-CDS:
BAE33690.1,
AAI38587.1,
AAI71958.1,
AAB51250.1
Ensembl_TRS:
ENSMUST00000025906
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025906
RefSeq:
XP_017173698.1,
XP_030106810.1,
XP_006527174.1,
NP_031979.2
|
| Others |
UniRef100:
UniRef100_O08580
UniRef90:
UniRef90_O08580
UniRef50:
UniRef50_P11474
UniGene:
Mm.386776
CCDS:
CCDS29509.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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