| Type | Description |
|---|---|
| Definition | gastrulation brain homeobox 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 12:28:00 | Gastrulation brain homeobox 2 (GBX2) methylation is associated with Gleason score (GS), pathologic stage (pT), and biochemical recurrence (BCR) in prostate cancer (PCa). Among intraductal carcinoma/cribriform architecture (IDC/C)-negative patients, GBX2 methylation improves prediction of BCR. Loss of TET2 in prostate cells results in greater GBX2 methylation. | 31200836 |
| 2014-09-04 14:41:00 | The accession number for the cDNA listed for the sequence data at the bottom of page 335 on the left side is incorrect. It should read U31468 instead of U31458. | 8838315 |
| 2013-12-21 11:17:00 | Data established a seven-gene (AR, ESR2, GATA3, GBX2, KRT16, MMP28 and WNT11) prognostic signature to define a subset of triple-negative breast cancer (TNBC). | 23549873 |
| 2010-04-07 21:39:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors | 17060451 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GBX2_HUMAN,
F8VY47_HUMAN
UniprotKB:
P52951,
F8VY47
UniParc:
UPI00020CDF70,
UPI000012B273
EMBL:
BC137449,
CH471063,
BC137448,
AC079135,
U31468,
AF118452,
U02080
Ensembl:
ENSG00000168505
KO:
hsa:2637
|
| Nucleutide sequences |
EMBL-CDS:
EAW71084.1,
AAI37449.1,
AAA17406.1,
AAD39907.1,
AAI37450.1,
AAX93240.1,
AAC03241.1
Ensembl_TRS:
ENST00000306318,
ENST00000551105
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000302251,
ENSP00000448747
RefSeq:
NP_001476.2,
NP_001288616.1
|
| Others |
UniRef100:
UniRef100_P52951,
UniRef100_F8VY47
UniRef90:
UniRef90_P52951,
UniRef90_F8VY47
UniRef50:
UniRef50_P48031,
UniRef50_F8VY47
UniGene:
Hs.184945
CCDS:
CCDS2515.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31200836 |
Eur Urol Oncol Renu Jeyapala , Andrea J Savio , Ekaterina Olkhov-Mitsel , Shivani Kamdar , Fang Zhao , Carmelle Cuizon , Richard S C Liu , Alex Zlotta , Neil Fleshner , Theodorus van der Kwast , Bharati Bapat |
2019-05-01 | - |
| 28473536 |
Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science Yimeng Yin , Ekaterina Morgunova , Arttu Jolma , Eevi Kaasinen , Biswajyoti Sahu , Syed Khund-Sayeed , Pratyush K Das , Teemu Kivioja , Kashyap Dave , Fan Zhong , Kazuhiro R Nitta , Minna Taipale , Alexander Popov , Paul A Ginno , Silvia Domcke , Jian Yan , Dirk Schübeler , Charles Vinson , Jussi Taipale |
2017-05-05 | - |
| 26412852 |
Comprehensive comparative homeobox gene annotation in human and mouse. Database (Oxford) Laurens G Wilming , Veronika Boychenko , Jennifer L Harrow |
2015-01-01 |
Rhox7-ps2,
Obox4-ps1,
Obox4-ps2,
Obox4-ps3,
Obox4-ps4,
Obox4-ps5,
Obox4-ps6,
Obox4-ps7,
Obox4-ps10,
Obox4-ps24,
Obox4-ps25,
Obox4-ps26,
Obox4-ps32,
Obox4-ps34,
Obox4-ps36,
Obox4-ps37,
Obox4-ps38,
Obox4-ps39,
Cdx1,
Nobox,
Gbx1,
Rhox7a,
Rhox2-ps,
CDX1,
NOBOX,
GBX1,
GBX2,
MSX2P1
|
| 23722424 |
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science Cornelius A Rietveld , Sarah E Medland , Jaime Derringer , Jian Yang , Tõnu Esko , Nicolas W Martin , Harm-Jan Westra , Konstantin Shakhbazov , Abdel Abdellaoui , Arpana Agrawal , Eva Albrecht , Behrooz Z Alizadeh , Najaf Amin , John Barnard , Sebastian E Baumeister , Kelly S Benke , Lawrence F Bielak , Jeffrey A Boatman , Patricia A Boyle , Gail Davies , Christiaan de Leeuw , Niina Eklund , Daniel S Evans , Rudolf Ferhmann , Krista Fischer , Christian Gieger , HÃ¥kon K Gjessing , Sara Hägg , Jennifer R Harris , Caroline Hayward , Christina Holzapfel , Carla A Ibrahim-Verbaas , Erik Ingelsson , Bo Jacobsson , Peter K Joshi , Astanand Jugessur , Marika Kaakinen , Stavroula Kanoni , Juha Karjalainen , Ivana Kolcic , Kati Kristiansson , Zoltán Kutalik , Jari Lahti , Sang H Lee , Peng Lin , Penelope A Lind , Yongmei Liu , Kurt Lohman , Marisa Loitfelder , George McMahon , Pedro Marques Vidal , Osorio Meirelles , Lili Milani , Ronny Myhre , Marja-Liisa Nuotio , Christopher J Oldmeadow , Katja E Petrovic , Wouter J Peyrot , Ozren Polasek , Lydia Quaye , Eva Reinmaa , John P Rice , Thais S Rizzi , Helena Schmidt , Reinhold Schmidt , Albert V Smith , Jennifer A Smith , Toshiko Tanaka , Antonio Terracciano , Matthijs J H M van der Loos , Veronique Vitart , Henry Völzke , Jürgen Wellmann , Lei Yu , Wei Zhao , Jüri Allik , John R Attia , Stefania Bandinelli , François Bastardot , Jonathan Beauchamp , David A Bennett , Klaus Berger , Laura J Bierut , Dorret I Boomsma , Ute Bültmann , Harry Campbell , Christopher F Chabris , Lynn Cherkas , Mina K Chung , Francesco Cucca , Mariza de Andrade , Philip L De Jager , Jan-Emmanuel De Neve , Ian J Deary , George V Dedoussis , Panos Deloukas , Maria Dimitriou , Guðny EirÃksdóttir , Martin F Elderson , Johan G Eriksson , David M Evans , Jessica D Faul , Luigi Ferrucci , Melissa E Garcia , Henrik Grönberg , Vilmundur Guðnason , Per Hall , Juliette M Harris , Tamara B Harris , Nicholas D Hastie , Andrew C Heath , Dena G Hernandez , Wolfgang Hoffmann , Adriaan Hofman , Rolf Holle , Elizabeth G Holliday , Jouke-Jan Hottenga , William G Iacono , Thomas Illig , Marjo-Riitta Järvelin , Mika Kähönen , Jaakko Kaprio , Robert M Kirkpatrick , Matthew Kowgier , Antti Latvala , Lenore J Launer , Debbie A Lawlor , Terho Lehtimäki , Jingmei Li , Paul Lichtenstein , Peter Lichtner , David C Liewald , Pamela A Madden , Patrik K E Magnusson , Tomi E Mäkinen , Marco Masala , Matt McGue , Andres Metspalu , Andreas Mielck , Michael B Miller , Grant W Montgomery , Sutapa Mukherjee , Dale R Nyholt , Ben A Oostra , Lyle J Palmer , Aarno Palotie , Brenda W J H Penninx , Markus Perola , Patricia A Peyser , Martin Preisig , Katri Räikkönen , Olli T Raitakari , Anu Realo , Susan M Ring , Samuli Ripatti , Fernando Rivadeneira , Igor Rudan , Aldo Rustichini , Veikko Salomaa , Antti-Pekka Sarin , David Schlessinger , Rodney J Scott , Harold Snieder , Beate St Pourcain , John M Starr , Jae Hoon Sul , Ida Surakka , Rauli Svento , Alexander Teumer , LifeLines Cohort Study , Henning Tiemeier , Frank J A van Rooij , David R Van Wagoner , Erkki Vartiainen , Jorma Viikari , Peter Vollenweider , Judith M Vonk , Gérard Waeber , David R Weir , H-Erich Wichmann , Elisabeth Widen , Gonneke Willemsen , James F Wilson , Alan F Wright , Dalton Conley , George Davey-Smith , Lude Franke , Patrick J F Groenen , Albert Hofman , Magnus Johannesson , Sharon L R Kardia , Robert F Krueger , David Laibson , Nicholas G Martin , Michelle N Meyer , Danielle Posthuma , A Roy Thurik , Nicholas J Timpson , André G Uitterlinden , Cornelia M van Duijn , Peter M Visscher , Daniel J Benjamin , David Cesarini , Philipp D Koellinger |
2013-06-21 | - |
| 23549873 |
Clin. Cancer Res. Ke-Da Yu , Rui Zhu , Ming Zhan , Angel A Rodriguez , Wei Yang , Stephen Wong , Andreas Makris , Brian D Lehmann , Xi Chen , Ingrid Mayer , Jennifer A Pietenpol , Zhi-Ming Shao , W Fraser Symmans , Jenny C Chang |
2013-05-15 |
ESR2,
GATA3,
GBX2,
AR,
KRT16,
WNT11,
MMP28
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20237496 |
New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. S Davila , F E M Froeling , A Tan , C Bonnard , G J Boland , H Snippe , M L Hibberd , M Seielstad |
2010-04-01 |
SH2B3,
MICA,
NR1H3,
TSPAN2,
NAMPT,
PRG4,
KLRG1,
CD96,
EFS,
APC2,
LAMC3,
CRISP3,
TLR6,
CLEC10A,
SEMA4D,
CEBPG,
PROCR,
PRDX4,
IFI44,
CXCL13,
GNLY,
COLEC10,
SH2B2,
CD226,
TNFSF13B,
NFAT5,
KLRA1P,
CFHR4,
CFHR3,
C1QL1,
EDAR,
MAGED2,
PRDX3,
IFI44L,
LILRB5,
LILRB4,
LILRA1,
LILRA2,
DUS4L,
ESM1,
FGFR1OP,
FAF1,
CD160,
RASSF1,
IRAK3,
IL17F,
CHRM1,
CD300A,
COPE,
KIF12,
CMTM1,
SIGLEC11,
NLRP3,
TIRAP,
PGLYRP2,
PGLYRP3,
SLAMF6,
FCRL1,
FCRL3,
GBP4,
GBP5,
TNFRSF13C,
FOXP4,
IL22RA2,
DEFB118,
CLC,
ADD1,
SFXN4,
IFI27L1,
CCR3,
CCR4,
CCR5,
CCR7,
CCR8,
ACKR2,
CMKLR1,
CCDC78,
CD300LB,
OSCAR,
ANKLE1,
GABPB2,
CNTFR,
COL4A3,
COL4A4,
BPIFB6,
ZPLD1,
KLF6,
IL31RA,
PPARGC1B,
RAET1E,
ADORA2B,
SSC4D,
CR1,
PXDNL,
CR2,
CREB1,
CREM,
GAB3,
CRP
|
| 19274049 |
A census of human transcription factors: function, expression and evolution. Nat Rev Genet Juan M Vaquerizas , Sarah K Kummerfeld , Sarah A Teichmann , Nicholas M Luscombe |
2009-04-01 | - |
| 17060451 |
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors. Mol. Cell. Biol. Thomas Heimbucher , Christina Murko , Baubak Bajoghli , Narges Aghaallaei , Anja Huber , Ronald Stebegg , Dirk Eberhard , Maria Fink , Antonio Simeone , Thomas Czerny |
2007-01-01 | - |
| 15931389 |
J. Clin. Invest. Gennadi V Glinsky , Olga Berezovska , Anna B Glinskii |
2005-06-01 |
Bmi1,
NDC80,
CES1,
FGFR2,
USP22,
GBX2,
ANK3,
HCFC1,
MKI67,
RNF2,
BMI1,
BUB1,
CCNB1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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