| Type | Description |
|---|---|
| Definition | inhibitor of growth family, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 13:05:00 | ING1 knockdown leads to decreased expression of genes related to synaptic plasticity, including the regulatory subunit of calcineurin, Ppp3r1. In addition, ING1 binding at a site upstream of the transcription start site (TSS) of Ppp3r1 depends on yet another group of neuroepigenetic regulatory proteins, the Piwi-like family, which are also involved in DNA repair. | 29158107 |
| 2017-10-28 11:24:00 | Taken together, our findings provide evidence for a novel crosstalk and a crossregulation between ING1 and ING2 in regulating androgen receptor-mediated transactivation and suggest that ING2 acts as a novel corepressor that inhibits AR signaling, prostate cancer cell growth, and migration. | 27305909 |
| 2016-08-06 11:58:00 | ING1b is an important regulator of osteoblast differentiation and suppresses PPAR-beta/delta. | 26849833 |
| 2015-02-14 11:47:00 | Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1. | 24655373 |
| 2010-04-12 11:37:00 | Study reveals a novel connection between ING1 and a regulator of microRNA biogenesis and identifies new links between tumor suppressor proteins and the microRNA machinery. | 20179197 |
| Type | IDs |
|---|---|
| Synonymous | 2610028J21Rik, AA407184, AI875420, mING1h, p33Ing1, p37Ing1b |
| Gene |
UniProtKB-ID:
ING1_MOUSE,
Q3ULE3_MOUSE
UniprotKB:
Q9QXV3,
Q3ULE3
UniParc:
UPI0000029D42,
UPI000002A253
EMBL:
AK141466,
AF149820,
AF177755,
AK157424,
AF177756,
BC147784,
AF177757,
AF177753,
AK145553,
BC016573,
BC147770
Ensembl:
ENSMUSG00000045969
KO:
mmu:26356
|
| Nucleutide sequences |
EMBL-CDS:
AAF16911.1,
AAF16910.1,
AAF16909.1,
AAF09183.1,
AAH16573.1,
AAI47785.1,
AAF16908.1,
AAI47771.1,
BAE24693.1,
BAE34085.1,
BAE26505.1
Ensembl_TRS:
ENSMUST00000210041,
ENSMUST00000211007,
ENSMUST00000210740,
ENSMUST00000209565,
ENSMUST00000054399
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000147270,
ENSMUSP00000148030,
ENSMUSP00000147892,
ENSMUSP00000147476,
ENSMUSP00000062593
RefSeq:
NP_001289388.1,
NP_001289389.1,
NP_001289387.1,
NP_036049.2,
NP_001289380.1,
NP_001289386.1
|
| Others |
UniRef100:
UniRef100_Q9QXV3
UniRef90:
UniRef90_Q9QXV3
UniRef50:
UniRef50_Q9H160
UniGene:
Mm.25709
CCDS:
CCDS85499.1,
CCDS22097.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员