| Type | Description |
|---|---|
| Definition | heat shock protein family B (small) member 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:35:00 | Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels. | 32751642 |
| 2019-02-02 10:56:00 | HSPB8 binds BAG3 to promote spatial sequestration of ubiquitinated proteins. | 29405094 |
| 2018-12-01 11:25:00 | results strongly suggest that HSP22 represses HCC progression, especially HCC cell migration, by the down-regulation of the PI3K/AKT signaling pathway. | 28456666 |
| 2018-11-24 12:02:00 | We identified impaired RNA metabolism, secondary to TDP-43 loss of function, as a possible pathological mechanism of HSPB8 toxicity, leading to muscle and nerve degeneration | 29029362 |
| 2018-09-29 12:15:00 | Data indicated that the HSPB8 expression level was strongly positively correlated with MAPK signaling pathway and CREB pathway and worse prognosis. The methylation level of its DNA was negatively associated with its expression and positively associated with overall survival. These results suggest that HSPB8 could promote the proliferation and inhibit the apoptosis of GC cells by activating ERKCREB signaling. | 29693129 |
| Type | IDs |
|---|---|
| Synonymous | CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22 |
| Gene |
UniProtKB-ID:
HSPB8_HUMAN
UniprotKB:
Q9UJY1
UniParc:
UPI0000037C1B
EMBL:
CH471054,
AF191017,
AF133207,
BC002673,
BT006876,
AF217987,
AK312501,
CR533453,
AF250138,
AL136936
Ensembl:
ENSG00000152137
KO:
hsa:26353
|
| Nucleutide sequences |
EMBL-CDS:
AAH02673.1,
EAW98144.1,
AAF65562.1,
AAD55359.1,
BAG35403.1,
CAB66870.1,
AAP35522.1,
AAF09481.1,
AAG17230.1,
CAG38484.1
Gene_ORFName:
PP1629
Ensembl_TRS:
ENST00000281938
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000281938
RefSeq:
NP_055180.1
|
| Others |
UniRef100:
UniRef100_Q9UJY1
UniRef90:
UniRef90_Q9UJY1
UniRef50:
UniRef50_Q9UJY1
UniGene:
Hs.400095
CCDS:
CCDS9189.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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