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2633 GBP1

2633

GBP1

guanylate binding protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition guanylate binding protein 1

研究结论

Date Results Publications
2021-04-13 10:12:00 Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions. 32510692
2020-09-05 13:58:00 Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria. 32581219
2020-07-18 11:31:00 The alpha helix of the intermediate region is required for substrate-induced oligomerization and enhanced GMP production. 31954926
2020-06-20 11:09:00 GBP-1 may enhance lung adenocarcinoma invasiveness by promoting cell motility, and control of GBP-1 expression has the potential to contribute to the development of new therapeutic strategies for lung adenocarcinoma. 31421831
2020-01-11 12:33:00 transfection of GBP1 revealed its regulation on migration and invasiveness of glioma cells, decreasing sensitivity of chemotherapeutic agent, shortening survival of tumor-bearing animals. These data demonstrate that GBP1 may serve as a novel prognostic biomarker and a potential therapeutic target for gliomas. 29991124

名称对应

Type IDs
Gene
UniProtKB-ID: GBP1_HUMAN
UniprotKB: P32455
UniParc: UPI000013C9DF
EMBL: BT006847, M55542, AL160008, AK291783, CH471097, BC002666
Ensembl: ENSG00000117228
KO: hsa:2633
Nucleutide sequences
EMBL-CDS: AAA35871.1, AAH02666.1, AAP35493.1, BAF84472.1, EAW73148.1, EAW73150.1
Ensembl_TRS: ENST00000370473
Protein sequencees
Ensembl_PRO: ENSP00000359504
RefSeq: NP_002044.2, XP_024302119.1
Others
UniRef100: UniRef100_P32455
UniRef90: UniRef90_P32455
UniRef50: UniRef50_P32455
UniGene: Hs.62661
CCDS: CCDS718.1

全选

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研究热度

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