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26276 VPS33B

26276

VPS33B

VPS33B late endosome and lysosome associated

protein-coding

Homo sapiens

基因描述

Type Description
Definition VPS33B late endosome and lysosome associated

研究结论

Date Results Publications
2020-09-05 13:57:00 Mechanism of platelet alpha-granule biogenesis: study of cargo transport and the VPS33B-VPS16B complex in a model system. 31501156
2020-05-23 10:44:00 VPS33B is negatively regulated by LMP-1 and nicotine and thus suppresses the proliferation of nasopharyngeal carcinoma (NPC) cells by interacting with NESG1 to regulate EGFR/PI3K/AKT/c-Myc/P53/miR-133a-3p signaling in NPC cells. 30944308
2020-05-09 10:48:00 Results found VPS33B variation c.1726T>C, p.Cys576Arg to be associated with the attenuated phenotype of arthrogryposis, renal dysfunction, and cholestasis (ARC) syndrome. 31479177
2020-02-08 11:01:00 NESG1 also activated VPS33B expression via the RAS/ERK/c-Jun pathway. 31125123
2019-03-23 12:23:00 Down-regulation of Vps33b expression is a critical step for inflammation-driven hepatocellular carcinoma, and Vps33b serves as an important tumor suppressor in hepatocarcinogenesis. 29729199

名称对应

Type IDs
Gene
UniProtKB-ID: VP33B_HUMAN, F5H008_HUMAN, A0A0S2Z577_HUMAN, B7Z1N4_HUMAN
UniprotKB: Q9H267, F5H008, A0A0S2Z577, B7Z1N4
UniParc: UPI0001914AC2, UPI0000169A6E, UPI000015D95D, UPI00020654F0
EMBL: AL357472, CH471101, AF201694, AK293688, BC016445, AC068831, AF308803, KU178590, AK027754, AK074863
Ensembl: ENSG00000184056
KO: hsa:26276
Nucleutide sequences
EMBL-CDS: BAG52018.1, CAB93109.1, AAF91174.1, EAX02140.1, BAB55345.1, AAH16445.1, AAG34680.1, ALQ34048.1, EAX02139.1, BAH11570.1
Gene_ORFName: hCG_32582
Ensembl_TRS: ENST00000333371, ENST00000535906
Protein sequencees
Ensembl_PRO: ENSP00000327650, ENSP00000444053
RefSeq: XP_016877564.1, XP_005254944.1, XP_016877565.1, NP_001276078.1, NP_061138.3, NP_001276077.1, XP_011519750.1, XP_011519751.1
Others
UniRef100: UniRef100_F5H008, UniRef100_A0A2R8Z6Q0, UniRef100_Q9H267
UniRef90: UniRef90_Q9H267, UniRef90_E2RR76
UniRef50: UniRef50_Q9H267
UniGene: Hs.745007
CCDS: CCDS10369.1

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