| Type | Description |
|---|---|
| Definition | F-box protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 10:48:00 | in head and neck squamous cell carcinoma, fragile X mental retardation syndrome related protein 1 (Fxr1) overexpression correlates with reduced F-box protein 4 (Fbxo4) levels. | 29142209 |
| 2018-05-12 10:18:00 | FBXO4 is the E3 ubiquitin ligase to interact with and promote Mcl-1 ubiquitination and degradation. | 28776569 |
| 2014-06-28 12:50:00 | results define the impact of alternative splicing on Fbx4 function, and suggest that the attenuated cyclin D1 degradation by these novel Fbx4 isoforms provides a new insight for aberrant cyclin D1 expression in human cancers. | 24704453 |
| 2013-12-28 11:40:00 | The FBXO4 I377M mutant exhibits impaired cyclin D1 recruitment and ubiquitylation. | 24019069 |
| 2011-06-25 13:59:00 | 14-3-3varepsilon binds to Ser12-phosphorylated Fbx4 to mediate dimerization and function. | 21242966 |
| Type | IDs |
|---|---|
| Synonymous | FBX4 |
| Gene |
UniProtKB-ID:
FBX4_HUMAN,
D6RAJ6_HUMAN,
B3KNA0_HUMAN
UniprotKB:
Q9UKT5,
D6RAJ6,
B3KNA0
UniParc:
UPI000020CA1D,
UPI0000062307,
UPI000013E392,
UPI000015F6C8
EMBL:
AC034222,
BC048098,
CR749719,
AK024075,
AF129534,
AF176703
Ensembl:
ENSG00000151876
KO:
hsa:26272
|
| Nucleutide sequences |
EMBL-CDS:
CAH18486.1,
AAH48098.1,
AAF04468.1,
AAF03703.1,
BAG51262.1
Ensembl_TRS:
ENST00000296812,
ENST00000281623,
ENST00000509134
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296812,
ENSP00000281623,
ENSP00000421749
RefSeq:
NP_036308.1,
XP_011512328.1,
NP_277019.1,
XP_011512329.1,
XP_006714533.1,
NP_001284366.1
|
| Others |
UniRef100:
UniRef100_B3KNA0,
UniRef100_Q9UKT5,
UniRef100_D6RAJ6
UniRef90:
UniRef90_Q9UKT5-2,
UniRef90_Q9UKT5
UniRef50:
UniRef50_Q9UKT5-2,
UniRef50_Q9UKT5
UniGene:
Hs.165575
CCDS:
CCDS3938.1,
CCDS3939.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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