| Type | Description |
|---|---|
| Definition | F-box protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:41:00 | Fbxo6 confers drug-sensitization to cisplatin via inhibiting the activation of Chk1 in non-small cell lung cancer | 31140586 |
| 2020-04-11 12:43:00 | our studies have identified a general but, to our knowledge, previously unrecognized role and a novel noncanonical mechanism of FBXO6 in modulating IFN-I-mediated antiviral immune responses | 31308089 |
| 2019-11-16 12:02:00 | Fbxo6 is a novel regulator of mitosis by controlling chromosome separation via interacting with the spindle checkpoint proteins Mad2 and BubR1. | 30526252 |
| 2017-02-18 11:00:00 | FBXO6 as a functional E3 ubiquitin ligase for Ero1L that plays a critical role in inhibiting endoplasmic reticulum stress-induced apoptosis. | 27855403 |
| 2015-04-18 10:15:00 | It might inhibit cadmium-induced ER stress by functioning as a ubiquitin ligase in the ERAD system, thereby attenuating the cell death induced by subsequent JNK1 activation. | 25374377 |
| Type | IDs |
|---|---|
| Synonymous | FBG2, FBS2, FBX6, Fbx6b |
| Gene |
UniProtKB-ID:
FBX6_HUMAN
UniprotKB:
Q9NRD1
UniParc:
UPI000012A586
EMBL:
AF129536,
CH471130,
AF233223,
AL031731,
AK314989,
BC020880
Ensembl:
ENSG00000116663
KO:
hsa:26270
|
| Nucleutide sequences |
EMBL-CDS:
AAF67153.1,
EAW71696.1,
BAG37485.1,
AAF04470.1,
AAH20880.1
Ensembl_TRS:
ENST00000376753
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365944
RefSeq:
XP_006710634.1,
XP_005263505.1,
XP_016856496.1,
XP_011539534.1,
XP_005263506.1,
XP_005263508.1,
NP_060908.1
|
| Others |
UniRef100:
UniRef100_Q9NRD1
UniRef90:
UniRef90_Q9NRD1
UniRef50:
UniRef50_Q9NRD1
UniGene:
Hs.464419
CCDS:
CCDS133.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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