| Type | Description |
|---|---|
| Definition | F-box protein 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:05:00 | FBX8 promotes metastatic dormancy of colorectal cancer in liver. | 32796813 |
| 2020-05-23 12:25:00 | FBX8 directly targets GSTP1 for ubiquitin-mediated proteasome degradation in colorectal carcinoma. The inactivation of FBX8 negatively correlated with increased levels and stability of GSTP1 in clinical CRC tissues and FBX8 knockout transgenic mice. | 31024008 |
| 2017-10-14 12:45:00 | Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC. The preferential down-regulation of FBX8 in HCC patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC progression. | 23826080 |
| 2017-09-09 12:29:00 | FBX8 as a metastasis suppressor that functions through mTOR signaling pathway and has significant prognostic power. | 27916606 |
| 2015-09-12 10:47:00 | FBX8 down-expression was an independent prognostic indicator for glioma patient's survival. | 25550853 |
| Type | IDs |
|---|---|
| Synonymous | DC10, FBS, FBX8 |
| Gene |
UniProtKB-ID:
FBX8_HUMAN,
Q8IXA8_HUMAN,
A0A0S2Z5D1_HUMAN
UniprotKB:
Q9NRD0,
Q8IXA8,
A0A0S2Z5D1
UniParc:
UPI000012A588,
UPI00000743E7,
UPI0000EE2CC1
EMBL:
AY358721,
BC014679,
AF115514,
CH471056,
KU178588,
AF233224,
AF174596,
AC097653,
AF201932,
AK314483,
BC040456
Ensembl:
ENSG00000164117
KO:
hsa:26269
|
| Nucleutide sequences |
EMBL-CDS:
AAQ89083.1,
AAH40456.1,
AAH14679.1,
EAX04742.1,
AAF67154.1,
EAX04741.1,
AAF04517.1,
BAG37087.1,
EAX04744.1,
AAF86868.1,
AAO06951.1,
ALQ34046.1
Gene_ORFName:
UNQ1877/PRO4320,
DC10
Ensembl_TRS:
ENST00000503293,
ENST00000615392,
ENST00000393674
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000422905,
ENSP00000377280,
ENSP00000484517
RefSeq:
NP_036312.2,
XP_016863509.1
|
| Others |
UniRef100:
UniRef100_Q8IXA8,
UniRef100_Q9NRD0
UniRef90:
UniRef90_Q8IXA8,
UniRef90_Q9NRD0
UniRef50:
UniRef50_A0A0S7GG94,
UniRef50_Q9NRD0
UniGene:
Hs.76917
CCDS:
CCDS3820.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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