| Type | Description |
|---|---|
| Definition | F-box protein 22 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:54:00 | Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1alpha/VEGF pathway. | 30887251 |
| 2020-09-12 16:02:00 | Long noncoding RNA SNHG14 promotes osteosarcoma progression via miR-433-3p/FBXO22 axis. | 31948764 |
| 2020-08-01 12:03:00 | FBXO22 plays a tumor-promoting role by ubiquitylating and degrading nuclear PTEN. In accordance, FBXO22 is overexpressed in various cancer types, and contributes to nuclear PTEN downregulation in colorectal cancer tissues. | 32249768 |
| 2020-07-18 11:01:00 | FBXO22 is highly expressed in human lung adenocarcinoma and high FBXO22 expression predicts significant poor prognosis. | 31217475 |
| 2020-03-28 12:56:00 | SCF(FBXO22) targets HDM2 for degradation and possesses inhibitory effects against breast cancer tumor cell invasion and metastasis. | 31138683 |
| Type | IDs |
|---|---|
| Synonymous | FBX22, FISTC1 |
| Gene |
UniProtKB-ID:
FBX22_HUMAN
UniprotKB:
Q8NEZ5
UniParc:
UPI00021D6333,
UPI0000049FDF,
UPI000006DB13
EMBL:
AK024048,
AC027104,
AY005144,
BC032540,
BC039024,
BC020204,
BC041691,
AF174602
Ensembl:
ENSG00000167196
KO:
hsa:26263
|
| Nucleutide sequences |
EMBL-CDS:
AAH20204.2,
AAH32540.1,
AAF89095.1,
AAH41691.1,
AAH39024.1,
BAB14798.1,
AAF04523.1
Ensembl_TRS:
ENST00000308275,
ENST00000569022,
ENST00000453211
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307833,
ENSP00000396442,
ENSP00000457531
RefSeq:
XP_011519749.1,
NP_036302.1,
NP_671717.1
|
| Others |
UniRef100:
UniRef100_Q8NEZ5
UniRef90:
UniRef90_Q8NEZ5
UniRef50:
UniRef50_Q8NEZ5
UniGene:
Hs.591115
CCDS:
CCDS45310.1,
CCDS10287.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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