| Type | Description |
|---|---|
| Definition | GATA binding protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | Analysis of variants in GATA4 and FOG2/ZFPM2 demonstrates benign contribution to 46,XY disorders of sex development. | 31962012 |
| 2021-02-02 13:24:00 | Effect of GATA4 gene methylation on proliferation and apoptosis of SGC-7901 gastric cancer cells. | 32305051 |
| 2021-01-16 15:54:00 | Down-regulation of SOX17, GATA4 and FoxA2 promotes differentiation potential of hepatocytes from human hematopoietic stem cells. | 32433020 |
| 2020-07-18 11:22:00 | A dual luciferase reporter assay showed that both SRF mutants (G274D and G294C) impaired SRF transcriptional activity at the SRF promoter and atrial natriuretic factor (ANF) promoter (p < 0.05), additionally, the mutants displayed reduced synergism with GATA4. These results suggest that SRF-p.G274D and SRF-p.G294C may have potential pathogenic effects. | 32380971 |
| 2020-07-11 10:51:00 | Gata4 expression is downregulated in ectopic pancreatic tissue of some human biopsy samples | 31875961 |
| Type | IDs |
|---|---|
| Synonymous | ASD2, TACHD, TOF, VSD1 |
| Gene |
UniProtKB-ID:
GATA4_HUMAN,
B3KUF4_HUMAN,
B6DU75_HUMAN
UniprotKB:
P43694,
B3KUF4,
B6DU75
UniParc:
UPI000173A8B7,
UPI0000210220,
UPI00001B3DC4,
UPI0000210221
EMBL:
BC143479,
AC090790,
FJ169610,
AC069185,
L34357,
BC143434,
AY740706,
BC105108,
BC101580,
AK097060
Ensembl:
ENSG00000285109,
ENSG00000136574
KO:
hsa:2626
|
| Nucleutide sequences |
EMBL-CDS:
AAI05109.1,
AAW51922.1,
AAI43480.1,
AAI43435.1,
AAI01581.1,
AAA58496.1,
BAG53416.1,
ACI04537.1
Ensembl_TRS:
ENST00000335135,
ENST00000532059,
ENST00000647274,
ENST00000643249,
ENST00000528712,
ENST00000532977
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000495511,
ENSP00000435712,
ENSP00000334458,
ENSP00000493647,
ENSP00000435043,
ENSP00000473671
RefSeq:
XP_005272442.1,
NP_001295022.1,
XP_011542120.1,
NP_001361202.1,
NP_002043.2,
XP_011542119.1,
NP_001295023.1,
NP_001361203.1
|
| Others |
UniRef100:
UniRef100_B3KUF4,
UniRef100_A0A4W2H401,
UniRef100_P43694
UniRef90:
UniRef90_G1SH13,
UniRef90_A0A4W2H401,
UniRef90_P43694
UniRef50:
UniRef50_G1SH13,
UniRef50_Q08369,
UniRef50_A0A4W2H401
UniGene:
Hs.243987
CCDS:
CCDS5983.1,
CCDS78303.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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