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26230 TIAM2

26230

TIAM2

T cell lymphoma invasion and metastasis 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition T cell lymphoma invasion and metastasis 2

研究结论

Date Results Publications
2018-12-22 11:09:00 The authors show that the Rac1 selective guanine nucleotide exchange factor Sif and TIAM1-like Exchange Factor STEF, also known as TIAM2, localises to the nuclear envelope, co-localises with key perinuclear proteins and regulates the activity of perinuclear Rac1. 29844364
2017-06-03 11:58:00 Tiam2/Rac are key components of EphB2 trans-endocytosis and are important for cell repulsion. 27597758
2016-12-17 11:25:00 Results provide evidence that Sp1 positively controls TIAM2S transcription and that Sp1-mediated transcriptional activation is essential for TIAM2S ectopic expression in liver cancer cells. 26763486
2015-01-24 13:12:00 Knockdown of TIAM2 could up-regulate the expression of E-cadherin. 24377522
2012-06-02 11:09:00 TIAM2 expression was undetectable in normal human liver but was induced in all HCC cell lines and in 86% (78/91) of HCC biopsies. 21469146

名称对应

Type IDs
Synonymous STEF, TIAM-2
Gene
UniProtKB-ID: TIAM2_HUMAN, B3KW11_HUMAN
UniprotKB: Q8IVF5, B3KW11
UniParc: UPI00004A2468, UPI0001D14794, UPI0001AE72E6, UPI00004DF8BE, UPI000022CD11, UPI000013EEEC
EMBL: AK123859, AF120324, AL596202, AL122086, CH471051, BC066979, AK125459, AL355343, AF120323, AB095936, AL139101, BC137275
Ensembl: ENSG00000146426
KO: hsa:26230
Nucleutide sequences
EMBL-CDS: CAB59259.2, AAH66979.1, BAC86170.1, AAF05901.1, BAC23112.2, AAI37276.1, AAF05900.1, EAW47693.1, BAG53973.1
Ensembl_TRS: ENST00000360366, ENST00000456877, ENST00000529824, ENST00000275246, ENST00000461783
Protein sequencees
Ensembl_PRO: ENSP00000437188, ENSP00000433348, ENSP00000353528, ENSP00000407183, ENSP00000275246
RefSeq: NP_001371476.1, NP_001371475.1, NP_036586.3, NP_001010927.2
Others
UniRef100: UniRef100_B3KW11, UniRef100_Q8IVF5
UniRef90: UniRef90_A0A2K6MPJ3, UniRef90_Q8IVF5
UniRef50: UniRef50_Q8IVF5, UniRef50_Q6ZPF3
UniGene: Hs.586279
CCDS: CCDS34559.1, CCDS34558.1

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