| Type | Description |
|---|---|
| Definition | F-box and leucine rich repeat protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 12:34:00 | we conclude that homozygous FBXL3 LoF variants likely cause autosomal recessive ID, short stature, developmental delay and facial dysmorphism in humans, and that the Cys358Arg FBXL3 variant likely adds the circadian phenotype because of abnormal interaction with CRY1 and CRY2 | 30481285 |
| 2019-03-23 10:28:00 | FBXL3 was regulated by miR-4735-3p and suppressed cell proliferation and invasion in non-small cell lung cancer. | 30594330 |
| 2018-05-12 11:14:00 | data indicate an oncogenic role of miR-181d in CRC by promoting glycolysis, and miR-181d/CRY2/FBXL3/c-myc feedback loop might be a therapeutic target for patients with CRC. | 28749470 |
| 2017-11-04 10:38:00 | These results demonstrate that CRY2 stability controlled by FBXL3 plays a key role in the regulation of human sleep wake behavior. | 27529127 |
| 2017-09-02 11:21:00 | CRY2 and FBXL3 cooperatively degrade c-MYC preventing the development of cancer. | 27840026 |
| Type | IDs |
|---|---|
| Synonymous | FBL3, FBL3A, FBXL3A |
| Gene |
UniProtKB-ID:
FBXL3_HUMAN
UniprotKB:
Q9UKT7
UniParc:
UPI0000035C8B
EMBL:
BC072448,
AF126028,
AK314442,
AF129532
Ensembl:
ENSG00000005812
KO:
hsa:26224
|
| Nucleutide sequences |
EMBL-CDS:
AAF37383.1,
AAH72448.1,
AAF04466.1,
BAG37051.1
Ensembl_TRS:
ENST00000355619
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347834
RefSeq:
NP_036290.1,
XP_016876027.1,
XP_005266393.1,
XP_005266394.1
|
| Others |
UniRef100:
UniRef100_Q9UKT7
UniRef90:
UniRef90_Q8C4V4
UniRef50:
UniRef50_Q8C4V4
UniGene:
Hs.508284
CCDS:
CCDS9457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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