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2622 GAS8

2622

GAS8

growth arrest specific 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition growth arrest specific 8

研究结论

Date Results Publications
2020-10-31 13:19:00 Expression analysis of growth arrest specific 8 and its anti-sense in breast cancer tissues. 32165089
2020-02-01 12:34:00 The current study shows significance of GAS8 and GAS8-AS1 in the pathogenesis of MS and the putative role of GAS8-AS1 as a diagnostic biomarker in a subset of patients. 31003831
2019-06-01 10:08:00 Expression of GAS8-AS1 or GAS8 is significantly decreased in hepatocellular carcinoma tissues and is associated with a poor prognosis among hepatocellular carcinoma patients. 30228180
2018-10-27 10:29:00 In papillary thyroid carcinoma (PTC) cell lines, GAS8-AS1 inhibited proliferation, activated autophagy, and increased ATG5 expression. Downregulation of ATG5 reversed GAS8-AS1-mediated activation of autophagy leading to cell death, revealing a novel mechanism of the GAS8-AS1-ATG5 axis in PTC cell lines. 29327301
2017-12-16 11:21:00 Study identifies bi-allelic loss-of-function mutations in GAS8 as a cause for primary ciliary dyskinesia, and unveils the key importance of the protein encoded by this gene in N-DRC integrity and in the proper alignment of axonemal microtubules in humans. 27120127

名称对应

Type IDs
Synonymous CILD33, DRC4, GAS11
Gene
UniProtKB-ID: DRC4_HUMAN, B7Z1U9_HUMAN, A0A384MR00_HUMAN, A0A087WZT7_HUMAN
UniprotKB: O95995, B7Z1U9, A0A384MR00, A0A087WZT7
UniParc: UPI0000070A4C, UPI0000EE7DD0, UPI0001914C9B, UPI000387BE08
EMBL: AF050076, AK293958, AF050077, BC104785, BC112121, AF050071, AF050079, AC133919, AF050070, AK297857, AF050074, CH471184, AF050072, GQ891399, AF050069, AF050073, AK315261, AF050068, AF050075, AF050078
Ensembl: ENSG00000141013
KO: hsa:2622
Nucleutide sequences
EMBL-CDS: AAC69519.1, EAW66659.1, BAH12677.1, AAI04786.1, AAC69518.1, AAI12122.1, BAG37678.1, EAW66661.1, BAH11635.1, ADO22261.1
Ensembl_TRS: ENST00000268699, ENST00000536122, ENST00000620723
Protein sequencees
Ensembl_PRO: ENSP00000268699, ENSP00000440977, ENSP00000482877
RefSeq: NP_001273138.1, XP_016878614.1, NP_001273134.1, XP_005256366.1, XP_024305996.1, XP_011521294.1, XP_016878612.1, XP_006721238.1, XP_011521293.1, NP_001472.1, XP_016878611.1, XP_011521292.1, XP_016878613.1, NP_001273137.1
Others
UniRef100: UniRef100_O95995, UniRef100_B7Z1U9
UniRef90: UniRef90_O95995, UniRef90_G3SAE0
UniRef50: UniRef50_G3SAE0, UniRef50_O95995
UniGene: Hs.431792
CCDS: CCDS67101.1, CCDS10992.1

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