| Type | Description |
|---|---|
| Definition | F-box and WD repeat domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 10:19:00 | High FBXW2 expression is associated with drug resistance in lung cancer. | 31548378 |
| 2019-04-27 12:18:00 | Study demonstrates that FBXW2 inhibits tumor migration, invasion and metastasis in lung cancer cells by targeting beta-catenin for degradation. | 30918250 |
| 2018-11-17 10:20:00 | BTrCP-FBXW2-SKP2 axis forms an oncogene-tumour suppressor-oncogene cascade to control cancer cell growth with FBXW2 acting as a tumour suppressor by promoting SKP2 degradation. | 28090088 |
| 2013-09-21 12:29:00 | RACK1 competes with GCM1 for FBW2 and thereby prevents GCM1 ubiquitination, which is also supported by the observation that GCM1 is destabilized in RACK1-knockdown BeWo placental cells | 23651062 |
| 2010-01-21 00:00:00 | UBE2D2 is required for GCMa ubiquitination and for association with the SCF(FBXW2) complex. | 18703417 |
| Type | IDs |
|---|---|
| Synonymous | FBW2, Fwd2, Md6 |
| Gene |
UniProtKB-ID:
FBXW2_HUMAN,
B4DT60_HUMAN
UniprotKB:
Q9UKT8,
B4DT60
UniParc:
UPI000049299A,
UPI000049E0F3,
UPI000006FE3A
EMBL:
AF129531,
AL161911,
AF176698,
BC018738,
AK300066,
AK091860,
AK022484,
AF145024,
BC110334,
AF193594
Ensembl:
ENSG00000119402
KO:
hsa:26190
|
| Nucleutide sequences |
EMBL-CDS:
AAP97276.1,
AAH18738.1,
AAI10335.1,
BAG52430.1,
BAB14051.1,
AAF04465.1,
AAF13226.1,
AAP97280.1,
BAG61872.1
Ensembl_TRS:
ENST00000608872
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000476369
RefSeq:
NP_036296.2,
XP_016870104.1,
XP_006717112.1,
XP_016870106.1,
XP_006717114.1,
XP_016870105.1,
NP_001362817.1,
NP_001362818.1,
NP_001362819.1,
XP_024303277.1
|
| Others |
UniRef100:
UniRef100_Q9UKT8
UniRef90:
UniRef90_Q9UKT8
UniRef50:
UniRef50_Q9UKT8
UniGene:
Hs.494985
CCDS:
CCDS43872.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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